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Tazid 250mg Injection

Salt Composition: CEFTAZIDIME

₹67.00₹83.02

Inclusive of all taxes

Categories: Infectious Disease

Conditions: Antibacterials

Product Introduction

Tazid 250mg Injection contains ceftazidime as its active component. It is an antibiotic belonging to the cephalosporin class of drugs. This medication demonstrates broad-spectrum activity against Gram-negative bacteria, including Pseudomonas aeruginosa, Klebsiella species, Escherichia coli, Proteus species, and numerous others. It is used to treat various bacterial infections caused by susceptible organisms. Indications include lower respiratory tract infections, skin and skin structure infections, bone and joint infections, urinary tract infections, gynaecologic infections, bacterial septicaemia, abdominal infections, and central nervous system infections caused by various bacterial strains. This medicine may be combined with other antibiotics to produce synergistic effects and enhance overall treatment effectiveness in certain cases.

Patients with known allergy to cephalosporin antibiotics or penicillin antibiotics face an increased risk of allergic reactions to Tazid 250mg Injection. The medication is primarily excreted through the kidneys. Patients with impaired kidney function may require dose adjustments or close monitoring to prevent potential side effects or toxicity.

Gastrointestinal disturbances such as diarrhoea, colitis, or pseudomembranous colitis may occur. Patients with a history of gastrointestinal diseases require close monitoring during treatment with this medication.

Some formulations of Tazid 250mg Injection may contain ingredients not recommended for use in newborns and infants. A paediatrician should be consulted before administering any medication to young children.

Uses

Tazid 250mg Injection is used to treat the following: Respiratory tract infections Urinary tract infections Bone and joint infections Gynecologic infections Skin infections Abdominal infections Bacterial septicemia Infections in the nervous system

How it works

The therapeutic effect of Tazid 250mg Injection is its ability to effectively treat a wide range of serious bacterial infections, particularly those caused by Gram-negative bacteria. As a potent and broad-spectrum cephalosporin antibiotic, this medication works by inhibiting bacterial cell wall synthesis, leading to the destruction of susceptible bacteria. Its bactericidal action makes it a crucial choice in combating infections like complicated intra-abdominal infections, hospital-acquired pneumonia, bloodstream infections, urinary tract infections, and certain skin and soft tissue infections. Its intravenous formulation allows for rapid delivery and steady blood levels, making it well-suited for severe infections requiring immediate treatment.

How to Use

Tazid 250mg Injection is typically administered via injections in hospital settings by a healthcare professional. The dosage and frequency of administration depend on the severity of the infection, the patient's age, and kidney function.

Side Effects

Tazid 250mg Injection causes some side effects like all medications, although not everyone will experience them. Serious: Severe allergic reactions Severe skin reactions Clostridium difficile-associated diarrhea Liver problems (jaundice, dark urine, and persistent abdominal pain) Decreased urine output Swelling in the legs or ankles Changes in urination frequency Common: Nausea Vomiting Diarrhea Rash Itching Pain or inflammation at the injection site (for intravenous use) Headache Fever

Expert Tips

Patients with a history of allergies to cephalosporin or penicillin antibiotics should inform their healthcare provider to avoid potential allergic reactions. It is essential to complete the full course of treatment as prescribed, even if symptoms improve, to prevent antibiotic resistance. Tazid 250mg Injection can disrupt normal gut flora, leading to Clostridium difficile-associated diarrhea, so any signs of persistent diarrhea should be reported to the healthcare provider. Patients with impaired kidney or liver function may require dose adjustments or close monitoring. Since this medication can affect electrolyte levels, careful monitoring may be necessary, especially in high-risk patients. Use during pregnancy and breastfeeding requires careful evaluation by a healthcare professional to balance potential risks and benefits. Caution should be exercised in patients with central venous catheters to prevent catheter-related infections. Patients should promptly report any unusual or severe side effects to their healthcare provider.

References

  1. KD Tripathi, Essentials of Medical Pharmacology, Beta-Lactam Antibiotics, 7th edition, 2013,728.
  2. Goodman & Gilman’s, The Pharmacological Basics of Therapeutics, Penicillins, Cephalosporins and other Beta-Lactam Antibiotics, 12th edition, 2011, 1498.
  3. B. Braun Medical Inc., US Food and Drug Administration, [Revised on October 2021] [ Accessed on 21st July 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/050823s009lbl.pdf.
  4. Wockhardt UK Ltd, Electronic medicines compendium (EMC), [Revised on 16 Aug 2021] [ Accessed on 21st July 2023], https://www.medicines.org.uk/emc/files/pil.6346.pdf

Safety Advice

Pregnancy: Consult your doctor Pregnant women should inform their healthcare provider about their pregnancy status before starting treatment with Tazid 250mg Injection. The healthcare provider will carefully consider the specific circumstances and the severity of the infection before deciding to use this antibiotic during pregnancy.

Lungs: Consult your doctor Patients with lung infections or other respiratory conditions should consult their healthcare providers to ensure the appropriate use of Tazid 250mg Injection or any other medication.

Breastfeeding: Consult your doctor Tazid 250mg Injection can pass into breast milk, but the amount transferred is usually considered low. It is generally considered safe to use this medication while breastfeeding, especially in short courses or single doses. However, as a precaution, it is advisable to consult a healthcare professional before using this medication while breastfeeding.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS