Tbis 0.1% Ointment

Tbis 0.1% Ointment contains tacrolimus, an immunosuppressant medication belonging to the calcineurin inhibitor class. It is used to treat moderate to severe atopic dermatitis (eczema) in adults who cannot use alternative medications or whose eczema has not responded to other treatments. The medication suppresses immune system production of substances that may contribute to eczema development.

Do not use Tbis 0.1% Ointment if you are allergic to tacrolimus or any other ingredient in this medicine. Inform your doctor if you are allergic to any antibiotic group. Advise your doctor if you have or have had liver failure, skin problems, skin cancer, or a weakened immune system.

Contact your physician immediately if you develop fever, bruising under the skin (appearing as red dots), unexplained tiredness, confusion, yellowing of the skin or eyes, reduced urine output, vision loss, or seizures after using this medicine.

Limit sun and UV light exposure while using Tbis 0.1% Ointment by wearing protective clothing and applying sunscreen with a high sun protection factor, due to the potential risk of malignant skin changes with immunosuppressive therapy.

Do not apply this ointment to infected areas if you have infected lesions. If you notice any change in the appearance of your skin, contact your physician immediately.

This medicine is not approved for children younger than 16 years of age.

Moderate to severe atopic dermatitis (eczema)

Tbis 0.1% Ointment provides immunosuppression by inhibiting T-lymphocyte activation and proliferation and T-helper-cell-dependent B-cell response. It works by attaching to a protein called FKBP-12 and forms a complex called tacrolimus-FKBP, which inhibits the action of calcineurin phosphatase. This, in turn, inhibits the formation of T cells and suppresses the immune response.

This medicine is only for topical use. Always use Tbis 0.1% Ointment exactly as advised by your doctor. Apply the ointment as a thin layer to the affected areas of your skin. Avoid using the ointment inside your nose, mouth, or eyes. Before using the ointment, be sure your skin is completely dry. Your doctor will say the exact amount and time you should use this ointment. If you accidentally swallowed the ointment, contact your physician immediately and seek medical advice.

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Common Burning sensation and itching Redness, feeling or warmth Pain Increased skin sensitivity to hot and cold Skin tingling Rash Serious Acne Facial redness Eye infections Lentigo (flat brown spots on the skin) Cold sores Swelling of the hands, arms, feet, ankles, or lower legs

You may use moisturizing creams and lotions during the treatment with this ointment but remember that these products should not be used within two hours of applying Tbis 0.1% Ointment. Do not eat grapefruit or drink grapefruit juice while you are using tacrolimus. Do not drink alcohol while you are using this medicine. This medicine may interfere with the vaccine. Ask your healthcare professional before getting a flu shot or other vaccines. Apply sunscreen with a good SPF and wear protective clothing before you step out in the sun. Your doctor may advise you to take certain tests to monitor the effectiveness and side effects of the therapy. Keep all your appointments regularly.