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Tecum 0.1% Lotion 15ml

Salt Composition: TACROLIMUS

₹427.00₹501.56

Inclusive of all taxes

Tecum 0.1% Lotion 15ml

Categories: Nephrology

Conditions: Transplant

Product Introduction

Tecum 0.1% Lotion 15ml contains the active substance tacrolimus. It is an immunosuppressant that belongs to the class of medications called calcineurin inhibitors. Tecum 0.1% Lotion is used along with other medicines to prevent organ transplant rejection in patients receiving liver, kidney, heart, or other transplants. It is also indicated to control your body's immune response, enabling it to accept the transplanted organ. Do not use Tecum 0.1% Lotion if you are allergic to tacrolimus or any of the other ingredients of this medicine. Inform your doctor if you are allergic to any antibiotic group. Inform your doctor if you have had liver or heart disease before starting treatment. Notify your physician immediately if you develop fever, bruising under the skin (which may appear as red dots), unexplained tiredness, confusion, yellowing of the skin or eyes, reduced urine output, vision loss, and seizures after taking this medicine. Limit exposure to sunlight and UV light while using tacrolimus by wearing appropriate protective clothing and sunscreen with a high sun protection factor. Watch for skin changes with immunosuppressive therapy. This medicine may cause diarrhoea; inform your physician if you have diarrhoea lasting over a day. If you require any vaccinations, consult your doctor beforehand.

Uses

Tecum 0.1% Lotion 15ml uses Prevent organ transplant rejections.

How it works

Tecum 0.1% Lotion 15ml provides immunosuppression by inhibiting T-lymphocyte activation and proliferation and T-helper-cell-dependent B-cell response. It works by attaching to a protein called FKBP-12 and forms a complex called tacrolimus-FKBP, which inhibits the action of calcineurin phosphatase. This, in turn, inhibits the formation of T cells and suppresses the immune response.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Common Swelling in the arm or leg Hair loss Itchy skin Constipation, diarrhoea Nausea, vomiting Anemia Headache Cough Serious Increased or decreased heartbeats GI bleeding Liver Injury Seizure Acute kidney failure Lung infection or respiratory problems

Expert Tips

Avoid grapefruit and grapefruit juice while using Tecum 0.1% Lotion 15ml, as it may affect how the medicine works. Do not consume alcohol during treatment, as it may increase the risk of side effects. Check with your doctor before getting any vaccines, including flu shots, as this medicine may interfere with their effectiveness. Use this medicine as a long-term treatment to prevent organ rejection after a transplant. Do not stop using it without your doctor’s advice. Attend all scheduled medical tests and appointments to help your doctor monitor the treatment's effectiveness and detect any side effects early.

References

  1. Prograf 0.5mg Hard Ointments - Summary of Product Characteristics (SmPC) - (emc). www.medicines.org.uk. Published December 2022. Accessed May 25, 2023. https://www.medicines.org.uk/emc/product/6720/smpc
  2. Highlights Of Prescribing Information, Prograf ® (Tacrolimus) Ointments PROGRAF ® (Tacrolimus) Injection, (for Intravenous Use).; Revised 2012. Accessed May 25, 2023. https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/050709s031lbl.pdf
  3. Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Immunosuppressants, tolerogens, and immunostimulants, 12th edition, 2011, 1008.
  4. KD Tripathi, Essentials of Medical Pharmacology, Immunosuppressant drugs, 7th edition, 2013, 881.

Safety Advice

Pregnancy: Consult Your Doctor Based on animal studies, Tecum 0.1% Lotion 15ml can cause harmful effects on the baby. Inform your physician if you are pregnant, suspecting pregnancy or planning to get pregnant before initiating the treatment.

Lungs: Consult Your Doctor It is unknown whether Tecum 0.1% Lotion 15ml can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.

Breastfeeding: Unsafe Do not consume Tecum 0.1% Lotion 15ml if you are breastfeeding because this medicine is excreted into breast milk and may cause harmful effects on the body.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS