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Temodal 100mg Capsule

Salt Composition: TEMOZOLOMIDE

₹7978.00₹9515.36

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Temodal 100mg Capsule

Categories: Oncology

Conditions: Anti Cancer

Product Introduction

Temodal 100mg Capsule contains the active ingredient temozolomide. It is classified as an antitumor agent and is prescribed for brain cancer treatment, including glioblastoma multiforme in adults and malignant glioma (encompassing glioblastoma multiforme or anaplastic astrocytoma) in patients older than three years. Glioblastoma and anaplastic astrocytoma represent the most common and aggressive forms of brain cancer, typically associated with poor prognosis. Anaplastic astrocytoma is managed with Temodal 100mg Capsule or radiotherapy following biopsy. Glioblastoma multiforme is treated with combined radiotherapy and Temodal 100mg Capsule, continued as maintenance therapy thereafter.

Common side effects associated with Temodal 100mg Capsule include nausea, vomiting, dizziness, diarrhea, constipation, hair loss, rashes, tiredness, frequent urination, vision and hearing problems, elevated blood sugar levels, muscle damage, pain in muscles and joints, memory loss, coordination problems, infections, sleep disturbances and weight loss. Inform your doctor if any of these symptoms cause concern or persist.

Notify your physician if you are allergic to temozolomide or any components of this medication. Before beginning treatment, inform your doctor of any history of hepatitis B infection, anaemia, low platelet count, reduced RBC and WBC levels, blood clotting disorders, or liver or kidney disease. Your physician will undertake regular monitoring of WBC and platelet counts. Do not take this medication if you are pregnant or breastfeeding. Both women and men must use effective birth control to prevent pregnancy and fathering of a child.

Uses

Treatment of newly diagnosed glioblastoma multiforme. Treatment of refractory anaplastic astrocytoma

How it works

Temodal 100mg Capsule acts by inhibiting the production of genetic material (DNA and RNA) of the cancer cells, which results in preventing their cell growth and multiplication, thereby preventing cancer spread to other parts of the body.

How to Use

Use as directed by your physician. Your physician will prescribe an adequate dose according to your height and weight. Swallow the capsule whole with a glass of water, on an empty stomach. Do not open, crush or chew the capsule and avoid contact of the open capsules with your skin.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious: Secondary cancer like myelodysplastic syndrome and myeloid leukemia. Severe Allergic reactions Inflammation and fluid buildup in lungs Blood clot in lungs or legs Liver toxicity Convulsions Fever and chills Severe headache Uncontrolled bleeding Common: Hair loss Rashes Tiredness Nausea, vomiting and diarrhea Constipation High blood sugar levels Dizziness, impaired sensation, tingling sensation, abnormal taste Vision and Hearing problem Frequent urination Muscle damage, pain in muscles and joints Weight changes Infections and wounds Amnesia Abnormal blood cell counts Loss of appetite Sleep problems Memory loss Difficulty concentrating, changes in mental status and alertness Coordination problems

Expert Tips

It is advised to use effective birth control for both men and women taking Temodal 100mg Capsule. Women of reproductive potential must use effective contraception during and after six months of therapy. Male patients receiving Temodal 100mg Capsule treatment should refrain from fathering children and should use reliable contraception during and for three months following the treatment. Your doctor could suggest routine blood tests to check your electrolyte levels, blood cell count, and liver function.

References

  1. 1. Sun Pharmaceutical Industries, Electronic Medicines Compendium (EMC) [Revised on Feb 2022] [Accessed on 21 Nov 2022] https://www.medicines.org.uk/emc/files/pil.5318.pdf 2. Pfizer, US Food and Drug Administration, [Revised on Sep 2015] [Accessed on 21 Nov 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/021029s031lbl.pdf 3. Neha Singh et al., Mechanisms of temozolomide resistance in glioblastoma - a comprehensive review, Cancer Drug Resist; Published on Mar 2021; Accessed on 21/09/2022; https://cdrjournal.com/article/view/3779 4. Zerong Tian et al., Glioblastoma and Anaplastic Astrocytoma: Differentiation Using MRI Texture Analysis, Front. Oncol., Published on Sep 2019; Accessed on 21/09/2022; https://www.frontiersin.org/articles/10.3389/fonc.2019.00876/full

Safety Advice

Pregnancy: unsafe Temodal 100mg Capsule is unsafe to use during pregnancy as it may cause fetal harm. It should not be used unless prescribed by your physician. Women with childbearing potential should use effective contraceptive precautions for at least 6 months following the completion of treatment.

Lungs: Consult your doctor Inform your physician before taking Temodal 100mg Capsule if you have if you have any lung conditions.

Breastfeeding: unsafe Temodal 100mg Capsule is unsafe to use during breastfeeding as it passes through breast milk and harm the baby. Consult your physician for advice before breastfeeding.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS