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Temonat 20mg Capsule
Salt Composition: TEMOZOLOMIDE
- Manufacturer: NATCO PHARMA LTD
- Pack Size: 5 CAPSULE(s) IN A STRIP
- Dosage Form: CAPSULE
- Strength: 20MG
- Prescription Required
- Storage: Keep Temonat 20mg Capsule out of sight and reach of children. Store protected from light and moisture. Do not store above 25°C.
₹1167.00₹8437.50
Inclusive of all taxes
Product Introduction
Temonat 20mg Capsule contains Temozolomide, an antitumor medicine used to treat brain cancers, including glioblastoma multiforme (GBM) in adults and malignant glioma, such as glioblastoma multiforme and anaplastic astrocytoma, in patients older than three years. It is an oral alkylating agent that works by slowing or stopping the growth of cancer cells. In newly diagnosed glioblastoma, Temonat 20mg Capsule is commonly used in combination with radiotherapy, followed by maintenance therapy. For anaplastic astrocytoma, it may be prescribed after biopsy or when previous treatments have not been successful. The dosage is determined by the oncologist based on the patient's age, body weight, medical condition, and treatment response. The capsule should be swallowed whole with water and taken exactly as prescribed.
Common side effects of Temonat 20mg Capsule include nausea, vomiting, loss of appetite, fatigue, headache, constipation, hair loss, dizziness, skin rash, infections, and reduced blood cell counts, which may increase the risk of bleeding or infections. Serious side effects, such as liver problems or severe bone marrow suppression, require immediate medical attention. Do not take this medicine if you are allergic to Temozolomide or any of its ingredients. Before starting treatment, inform your doctor if you have hepatitis B infection, anaemia, low red or white blood cell counts, low platelet count, bleeding disorders, or liver or kidney disease. Regular blood tests are essential to monitor blood cell counts and liver function throughout treatment. Temonat 20mg Capsule should not be used during pregnancy or breastfeeding, and both men and women should use effective contraception during treatment and for the duration recommended by their healthcare provider.
Uses
Temonat 20mg uses are Treatment of newly diagnosed glioblastoma multiforme. Treatment of refractory anaplastic astrocytoma
How it works
Temonat 20mg Capsule acts by inhibiting the production of genetic material (DNA and RNA) of the cancer cells, which results in preventing their cell growth and multiplication, thereby preventing cancer spread to other parts of the body.
How to Use
Use as directed by your physician. Your physician will prescribe an adequate dose according to your height and weight. Swallow the capsule whole with a glass of water, on an empty stomach. Do not open, crush or chew the capsule and avoid contact of the open capsules with your skin.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Temonat 20mg side effects are Serious: Secondary cancer like myelodysplastic syndrome and myeloid leukemia. Severe Allergic reactions Inflammation and fluid buildup in lungs Blood clot in lungs or legs Liver toxicity Convulsions Fever and chills Severe headache Uncontrolled bleeding Common: Hair loss Rashes Tiredness Nausea, vomiting and diarrhea Constipation High blood sugar levels Dizziness, impaired sensation, tingling sensation, abnormal taste Vision and Hearing problem Frequent urination Muscle damage, pain in muscles and joints Weight changes Infections and wounds Amnesia Abnormal blood cell counts Loss of appetite Sleep problems Memory loss Difficulty concentrating, changes in mental status and alertness Coordination problems
Expert Tips
Both men and women taking Temonat 20mg Capsule should use effective birth control. Women of reproductive potential must use contraception during treatment and for six months after therapy. Men receiving Temonat 20mg Capsule should avoid fathering children and use reliable contraception during treatment and for three months after therapy. Doctors may recommend routine blood tests to monitor: Electrolyte levels Blood cell count Liver function.
References
- 1. Sun Pharmaceutical Industries, Electronic Medicines Compendium (EMC) [Revised on Feb 2022] [Accessed on 21 Nov 2022] https://www.medicines.org.uk/emc/files/pil.5318.pdf 2. Pfizer, US Food and Drug Administration, [Revised on Sep 2015] [Accessed on 21 Nov 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/021029s031lbl.pdf 3. Neha Singh et al., Mechanisms of temozolomide resistance in glioblastoma - a comprehensive review, Cancer Drug Resist; Published on Mar 2021; Accessed on 21/09/2022; https://cdrjournal.com/article/view/3779 4. Zerong Tian et al., Glioblastoma and Anaplastic Astrocytoma: Differentiation Using MRI Texture Analysis, Front. Oncol., Published on Sep 2019; Accessed on 21/09/2022; https://www.frontiersin.org/articles/10.3389/fonc.2019.00876/full
Safety Advice
Pregnancy: unsafe Temonat 20mg Capsule is unsafe to use during pregnancy as it may cause fetal harm. It should not be used unless prescribed by your physician. Women with childbearing potential should use effective contraceptive precautions for at least 6 months following the completion of treatment.
Lungs: Consult your doctor Inform your physician before taking Temonat 20mg Capsule if you have if you have any lung conditions.
Breastfeeding: unsafe Temonat 20mg Capsule is unsafe to use during breastfeeding as it passes through breast milk and harm the baby. Consult your physician for advice before breastfeeding.
Disclaimer
The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.