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Temonat 250mg Capsule
Salt Composition: TEMOZOLOMIDE
- Manufacturer: NATCO PHARMA LTD
- Pack Size: 5 CAPSULE(s) IN A BOTTLE
- Dosage Form: CAPSULE
- Strength: 250MG
- Prescription Required
- Storage: Keep Temonat 250mg Capsule out of sight and reach of children. Store protected from light and moisture. Do not store above 25°C.
₹4772.00₹21562.50
Inclusive of all taxes
Product Introduction
Temonat 250mg capsule contains the active ingredient temozolomide and belongs to the class of antitumor agents. It is prescribed to treat brain cancers such as glioblastoma multiforme in adults and malignant glioma, including glioblastoma multiforme or anaplastic astrocytoma in patients older than three years. Glioblastoma and anaplastic astrocytoma are among the most common and aggressive brain cancers with low survival rates. Anaplastic astrocytoma is treated with Temonat 250mg Capsule or radiotherapy following biopsy. Glioblastoma multiforme is treated with a combination of radiotherapy and Temonat 250mg Capsule, continued as maintenance therapy.
Common side effects associated with Temonat 250mg Capsule include nausea, vomiting, dizziness, diarrhoea, constipation, hair loss, rashes, fatigue, frequent urination, vision and hearing problems, elevated blood sugar levels, muscle damage, pain in muscles and joints, memory loss, coordination problems, infections, sleep disturbances and weight loss. Inform your doctor if any of these symptoms affect you or persist.
Temonat 250mg substitutes include temozolomide generic capsules or Temodal 250mg Capsule. Inform your physician if you are allergic to Temonat 250mg Capsule or any of its ingredients. Before starting treatment, notify your physician if you have hepatitis B infection, anaemia, low platelet count, low red blood cell and white blood cell levels, blood clotting problems, or any liver or kidney complications. Your physician will monitor your white blood cell and platelet counts regularly. Avoid this medication if you are pregnant or breastfeeding. Both women and men should use effective contraception to prevent pregnancy.
Uses
Temonat 250mg uses are: Treatment of newly diagnosed glioblastoma multiforme. Treatment of refractory anaplastic astrocytoma
How it works
Temonat 250mg Capsule acts by inhibiting the production of genetic material (DNA and RNA) of the cancer cells, which results in preventing their cell growth and multiplication, thereby preventing cancer spread to other parts of the body.
How to Use
Use as directed by your physician. Your physician will prescribe an adequate Temonat 250 mg dosage according to your height and weight. Swallow the capsule whole with a glass of water, on an empty stomach. Do not open, crush or chew the capsule and avoid contact of the open capsules with your skin.
Side Effects
Temonat 250mg side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious: Secondary cancer like myelodysplastic syndrome and myeloid leukemia. Severe Allergic reactions Inflammation and fluid buildup in lungs Blood clot in lungs or legs Liver toxicity Convulsions Fever and chills Severe headache Uncontrolled bleeding Common: Hair loss Rashes Tiredness Nausea, vomiting and diarrhea Constipation High blood sugar levels Dizziness, impaired sensation, tingling sensation, abnormal taste Vision and Hearing problem Frequent urination Muscle damage, pain in muscles and joints Weight changes Infections and wounds Amnesia Abnormal blood cell counts Loss of appetite Sleep problems Memory loss Difficulty concentrating, changes in mental status and alertness Coordination problems
References
- 1. Sun Pharmaceutical Industries, Electronic Medicines Compendium (EMC) [Revised on Feb 2022] [Accessed on 21 Nov 2022] https://www.medicines.org.uk/emc/files/pil.5318.pdf 2. Pfizer, US Food and Drug Administration, [Revised on Sep 2015] [Accessed on 21 Nov 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/021029s031lbl.pdf 3. Neha Singh et al., Mechanisms of temozolomide resistance in glioblastoma - a comprehensive review, Cancer Drug Resist; Published on Mar 2021; Accessed on 21/09/2022; https://cdrjournal.com/article/view/3779 4. Zerong Tian et al., Glioblastoma and Anaplastic Astrocytoma: Differentiation Using MRI Texture Analysis, Front. Oncol., Published on Sep 2019; Accessed on 21/09/2022; https://www.frontiersin.org/articles/10.3389/fonc.2019.00876/full
Safety Advice
Pregnancy: unsafe Temonat 250mg Capsule is unsafe to use during pregnancy as it may cause fetal harm. It should not be used unless prescribed by your physician. Women with childbearing potential should use effective contraceptive precautions for at least 6 months following the completion of treatment.
Lungs: Consult your doctor Inform your physician before taking Temonat 250mg Capsule if you have if you have any lung conditions.
Breastfeeding: unsafe Temonat 250mg Capsule is unsafe to use during breastfeeding as it passes through breast milk and harm the baby. Consult your physician for advice before breastfeeding.
Disclaimer
The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.