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Temosted 20mg Capsule

Salt Composition: TEMOZOLOMIDE

₹844.00₹2066.25

Inclusive of all taxes

Categories: Oncology

Conditions: Anti Cancer

Product Introduction

Temosted 20mg Capsule contains the active ingredient Temozolomide, an antitumor agent. It is prescribed for brain tumours in adults and paediatric patients older than three years, including glioblastoma multiforme and malignant glioma such as anaplastic astrocytoma. Glioblastoma and anaplastic astrocytoma are aggressive brain tumours with limited survival outcomes. Anaplastic astrocytoma is managed with Temosted 20mg Capsule or radiotherapy following biopsy. Glioblastoma multiforme is treated with a combination of radiotherapy and Temosted 20mg Capsule, with continuation as maintenance therapy.

Common side effects associated with Temosted 20mg Capsule include nausea, vomiting, dizziness, diarrhoea, constipation, hair loss, rashes, tiredness, frequent urination, vision and hearing problems, elevated blood glucose levels, muscle damage, muscle and joint pain, memory loss, coordination difficulties, infections, sleep disturbances and weight loss. Inform your doctor if any of these symptoms occur or persist.

Inform your physician if you are allergic to Temosted 20mg Capsule or any of its ingredients. Before commencing treatment, advise your doctor if you have hepatitis B infection, anaemia, low platelet count, reduced red blood cell or white blood cell levels, blood clotting disorders, or liver or kidney problems. Your physician will monitor your white blood cell and platelet counts regularly.

Avoid this medication if you are pregnant or breastfeeding. Both women and men should use contraception to prevent pregnancy and fathering a child.

Uses

Treatment of newly diagnosed glioblastoma multiforme. Treatment of refractory anaplastic astrocytoma.

How it works

Temosted 20mg Capsule acts by inhibiting the production of genetic material (DNA and RNA) of the cancer cells, which results in preventing their cell growth and multiplication, thereby preventing cancer spread to other parts of the body.

How to Use

This medicine is given only in a hospital by a healthcare provider. Your doctor will recommend the dosage and frequency of Temosted 20mg Capsule.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious: Secondary cancer like myelodysplastic syndrome and myeloid leukemia. Severe Allergic reactions Inflammation and fluid buildup in lungs Blood clot in lungs or legs Liver toxicity Convulsions Fever and chills Severe headache Uncontrolled bleeding Common: Hair loss Rashes Tiredness Nausea, vomiting and diarrhea Constipation High blood sugar levels Dizziness, impaired sensation, tingling sensation, abnormal taste Vision and Hearing problem Frequent urination Muscle damage, pain in muscles and joints Weight changes Infections and wounds Amnesia Abnormal blood cell counts Loss of appetite Sleep problems Memory loss Difficulty concentrating, changes in mental status and alertness Coordination problems

Expert Tips

It is advised to use effective birth control for both men and women taking Temosted 20mg Capsule. Women of reproductive potential must use effective contraception during and after six months of therapy. Male patients receiving Temosted 20mg Capsule treatment should refrain from fathering children and should use reliable contraception during and for three months following the treatment. Your doctor could suggest routine blood tests to check your electrolyte levels, blood cell count, and liver function.

References

  1. Sun Pharmaceutical Industries, Electronic Medicines Compendium (EMC) [Revised on Feb 2022] [Accessed on 21 Nov 2022] https://www.medicines.org.uk/emc/files/pil.5318.pdf
  2. Pfizer, US Food and Drug Administration, [Revised on Sep 2015] [Accessed on 21 Nov 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/021029s031lbl.pdf
  3. Neha Singh et al., Mechanisms of temozolomide resistance in glioblastoma - a comprehensive review, Cancer Drug Resist; Published on Mar 2021; Accessed on 21/09/2022; https://cdrjournal.com/article/view/3779
  4. Zerong Tian et al., Glioblastoma and Anaplastic Astrocytoma: Differentiation Using MRI Texture Analysis, Front. Oncol., Published on Sep 2019; Accessed on 21/09/2022; https://www.frontiersin.org/articles/10.3389/fonc.2019.00876/full

Safety Advice

Pregnancy: unsafe Temosted 20mg Capsule is unsafe to use during pregnancy as it may cause fetal harm. It should not be used unless prescribed by your physician. Women with childbearing potential should use effective contraceptive precautions for at least 6 months following the completion of treatment.

Lungs: Consult your doctor Inform your physician before taking Temosted 20mg Capsule if you have severe lungs problems. Dose adjustment is required based on the condition.

Breastfeeding: unsafe Temosted 20mg Capsule is unsafe to use during breastfeeding as it passes through breast milk and harm the baby. Consult your physician for advice before breastfeeding.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS