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Temother 250mg Capsule

Salt Composition: TEMOZOLOMIDE

₹3938.00₹18750.00

Inclusive of all taxes

Categories: Oncology

Conditions: Anti Cancer

Product Introduction

Temother 250mg Capsule contains temozolomide as the active ingredient. It is an antitumor agent used to treat brain cancers including glioblastoma multiforme in adults and malignant glioma, including glioblastoma multiforme or anaplastic astrocytoma in patients older than three years. Glioblastoma and anaplastic astrocytoma are aggressive brain cancers associated with low survival rates. Anaplastic astrocytoma is treated with Temother 250mg Capsule or radiotherapy following biopsy. Glioblastoma multiforme is treated with a combination of radiotherapy and Temother 250mg Capsule, continued as maintenance therapy.

Common side effects associated with Temother 250mg Capsule include nausea, vomiting, dizziness, diarrhea, constipation, hair loss, rashes, tiredness, frequent urination, vision and hearing problems, elevated blood sugar levels, muscle damage, muscle and joint pain, memory loss, coordination problems, infections, sleep disturbances and weight loss. Inform your doctor if any of these symptoms occur or persist.

Inform your physician if you are allergic to Temother 250mg Capsule or its ingredients. Before beginning treatment, notify your physician if you have hepatitis B infection, anemia, low platelet count, low red blood cell and white blood cell levels, blood clotting problems, or any liver or kidney problems. Your physician will monitor your white blood cell and platelet counts regularly.

Avoid this medication if you are pregnant or breastfeeding. Both women and men should use birth control to prevent pregnancy and to avoid fathering a child.

Uses

Treatment of newly diagnosed glioblastoma multiforme. Treatment of refractory anaplastic astrocytoma

How it works

Temother 250mg Capsule acts by inhibiting the production of genetic material (DNA and RNA) of the cancer cells, which results in preventing their cell growth and multiplication, thereby preventing cancer spread to other parts of the body.

How to Use

Use as directed by your physician. Your physician will prescribe an adequate dose according to your height and weight. Swallow the capsule whole with a glass of water, on an empty stomach. Do not open, crush or chew the capsule and avoid contact of the open capsules with your skin.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious: Secondary cancer like myelodysplastic syndrome and myeloid leukemia. Severe Allergic reactions Inflammation and fluid buildup in lungs Blood clot in lungs or legs Liver toxicity Convulsions Fever and chills Severe headache Uncontrolled bleeding Common: Hair loss Rashes Tiredness Nausea, vomiting and diarrhea Constipation High blood sugar levels Dizziness, impaired sensation, tingling sensation, abnormal taste Vision and Hearing problem Frequent urination Muscle damage, pain in muscles and joints Weight changes Infections and wounds Amnesia Abnormal blood cell counts Loss of appetite Sleep problems Memory loss Difficulty concentrating, changes in mental status and alertness Coordination problems

Expert Tips

It is advised to use effective birth control for both men and women taking Temother 250mgg Capsule. Women of reproductive potential must use effective contraception during and after six months of therapy. Male patients receiving Temother 250mg Capsule treatment should refrain from fathering children and should use reliable contraception during and for three months following the treatment. Your doctor could suggest routine blood tests to check your electrolyte levels, blood cell count, and liver function.

References

  1. 1. Sun Pharmaceutical Industries, Electronic Medicines Compendium (EMC) [Revised on Feb 2022] [Accessed on 21 Nov 2022] https://www.medicines.org.uk/emc/files/pil.5318.pdf 2. Pfizer, US Food and Drug Administration, [Revised on Sep 2015] [Accessed on 21 Nov 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/021029s031lbl.pdf 3. Neha Singh et al., Mechanisms of temozolomide resistance in glioblastoma - a comprehensive review, Cancer Drug Resist; Published on Mar 2021; Accessed on 21/09/2022; https://cdrjournal.com/article/view/3779 4. Zerong Tian et al., Glioblastoma and Anaplastic Astrocytoma: Differentiation Using MRI Texture Analysis, Front. Oncol., Published on Sep 2019; Accessed on 21/09/2022; https://www.frontiersin.org/articles/10.3389/fonc.2019.00876/full

Safety Advice

Pregnancy: unsafe Temother 250mg Capsule is unsafe to use during breastfeeding as it passes through breast milk and harm the baby. Consult your physician for advice before breastfeeding.

Lungs: Consult your doctor Inform your physician before taking Temother 250mg Capsule if you have if you have any lung conditions.

Breastfeeding: Consult your doctor Avoid consuming alcohol while taking Temother 250mg Capsule as it may cause unpleasant side effects. Consult our doctor for advice.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS