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Themiset Injection
Salt Composition: PALONOSETRON
- Manufacturer: THEMIS MEDICARE LTD
- Pack Size: 1 VIAL(s) OF 5ML
- Dosage Form: INJECTION
- Strength: 0.25MG
- Prescription Required
- Storage: Store Themiset Injection in the original package at room temperature (25°C). Do not freeze. Keep it out of reach from children and pets. It is important to get the dose at the scheduled time. If you missed the schedule, contact your doctor and reschedule the dose.
₹129.00₹247.44
Inclusive of all taxes
Product Introduction
Themiset Injection is an antiemetic belonging to the 5-HT3 receptor antagonist class, containing Palonosetron as its active ingredient. It is indicated for prevention and treatment of nausea and vomiting caused by cancer treatments including chemotherapy, radiotherapy, or occurring after surgery. Nausea is characterised by stomach discomfort and the urge to vomit. Common side effects include hives, facial swelling, breathing difficulty, and chest pain. Inform your healthcare provider if these side effects are concerning or persist longer than expected. Administration may be given immediately or subsequently with anticancer medicines. Following surgery, it is typically administered up to 24 hours during recovery from anaesthesia. Consult your physician if you have a history of recurrent constipation, bowel obstruction, cardiac conditions, or electrolyte imbalance in your blood such as magnesium or potassium depletion. This medicine is contraindicated if you have an allergy to Palonosetron. Inform your physician of all medications you are currently taking, including herbal medicines and supplements, prior to receiving Themiset Injection.
Uses
Postoperative nausea and vomiting. Chemotherapy-induced nausea and vomiting.
How it works
It is a type of serotonin receptor antagonist, which works by blocking the action of serotonin in the body that induces nausea and vomiting. The chemotherapeutic trigger zone(CTZ) contains the receptor serotonin, when this CTZ is stimulated, vomiting occurs. It prevents the signals from serotonin and helps to reduce the symptoms of nausea and vomiting.
How to Use
The medicine will be administered to you by a healthcare professional in a hospital setting. Themiset Injection is usually given about 30 minutes before you receive your anti-cancer medicine (chemotherapy) or right before anaesthesia for surgery.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious Hives Swollen face Breathing trouble Chest pain Common Headache Fatigue Dizziness Abdominal pain
Expert Tips
Talk to your physician if you have a history of repeated constipation, blockage in the bowel, heart problems, or imbalance of certain minerals (such as potassium and magnesium) in your blood before taking Themiset Injection Inform your doctor or nurse if you are taking any medicines that affect your heartbeat because they could cause a heartbeat problem when taken with this injection.
References
- Helsinn Birex Pharmaceuticals Ltd, Electronic medicines compendium (EMC), [Revised on Dec 2021] [ Accessed on 01st March 2023], https://www.medicines.org.uk/emc/files/pil.513.pdf
- Fresenius Kabi, US Food and Drug Administration, [Revised on Dec 2018] [Accessed on 01st March 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/208109s001lbl.pdf
- Goodman & Gilmanâs, The Pharmacological Basis of Therapeutics, Treatment of disorders of bowel motility and water flux, 12th edition, 2011, 1341.
- KD Tripathi, Essentials of Medical Pharmacology, Antiemetic, prokinetic and digestant drugs, 7th edition, 2013, 669.
Safety Advice
Pregnancy: Consult your doctor It is unknown whether Themiset Injection can be administered during pregnancy. Consult your doctor if you are pregnant or planning for pregnancy during the treatment.
Lungs: Consult your doctor It is not known whether Themiset Injection can be administered to patients with lung problems. Consult your doctor if you have any lung diseases before starting the treatment.
Breastfeeding: Consult your doctor It is not known if Themiset Injection passes into your breast milk or if it will affect your baby or your breast milk. Please consult your doctor before breastfeeding.
Disclaimer
The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.