Thioplan 15mg Injection

Thioplan 15mg Injection is an antineoplastic medication containing the active ingredient Thiotepa. It is prescribed in combination with other anti-cancer drugs before stem cell transplantation for adult patients with cancer in the lymph nodes of the central nervous system. It is used as preparation before stem cell transplant to reduce the risk of graft rejection. It controls the outflow within the cavity due to cancer in serous membranes. It is also indicated for treating breast, ovarian, and bladder cancer. The common side effects likely to be associated with Thioplan 15mg Injection are diarrhoea, rashes, bleeding, blood in urine, and cytomegalovirus infection. Inform your doctor if these side effects disturb or persist. Inform your healthcare provider if you are allergic or hypersensitive to Thioplan 15mg Injection and its ingredients. It is contraindicated in patients using a live virus or bacterial vaccine, including the yellow fever vaccine. If you have a history of cardiac, liver, kidney, and pulmonary disease and profound myelosuppression (anaemia, neutropenia, and thrombocytopenia), report to your doctor. Liver and cardiac function must be monitored regularly, and caution is advised in patients with cardiac disease and liver impairment. It is not recommended for use in pregnant and breastfeeding women.

Preparation for allogeneic hematopoietic stem cell transplantation in pediatric patients with class 3 beta-thalassemia Treatment of adenocarcinoma of breast and ovary. Treatment of superficial papillary cancer of the urinary bladder.

Thioplan 15mg Injection acts by damaging the genetic material (DNA and RNA) of the cancer cells. It stops the growth and multiplication of cancer by directly attacking DNA. This causes the breakage of DNA strands. The process of cross-linking is crucial in exhibiting toxicity in cancer cells. This leads to the exertion of cytotoxic effect and death of tumor cells.

Thioplan 15mg Injection should be administered by a qualified physician experienced in high-dose chemotherapy and stem cell transplant. Do not self-administer.

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious: Severe drop in blood cell count Heart problem Kidney damage Nerve damage Lung toxicity Liver toxicity Common: Cytomegalovirus infection Hemorrhage Diarrhea Blood in urine Rashes

It is advised to avoid ingestion, inhalation, or skin and eye contact. Skin reactions may occur with accidental exposure. Using gloves and protective clothing to prevent accidental skin contact is recommended. If the Thioplan 15mg Injection solution contacts the skin or mucosa, immediately wash the skin thoroughly with soap and water or rinse the mucosa with water and seek medical attention.