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Thromplat 50mg Tablet

Salt Composition: ELTROMBOPAG

₹3586.00₹4218.75

Inclusive of all taxes

Categories: Infectious Disease

Conditions: Anticoagulants

Product Introduction

Thromplat 50mg Tablet is an anticoagulant medicine that belongs to the thrombopoietin (TPO) receptor agonist class and contains the active ingredient Eltrombopag. It is used to treat low platelet counts associated with primary immune thrombocytopenia (ITP) or hepatitis C (HCV) infection. ITP is an autoimmune condition in which the body's immune system attacks and destroys platelets. Platelets are blood cells that help with clot formation and maintain the integrity of blood vessel walls. A reduced platelet count can lead to excessive bleeding and easy bruising. This tablet is also prescribed for adults with severe aplastic anaemia to manage low blood cell counts caused by the bone marrow's inability to produce sufficient new blood cells.

This medicine should not be taken by individuals who are allergic to Eltrombopag or any of the tablet's ingredients. Allergic reactions may vary from mild to severe and can include rash, itching, swelling, dizziness, or breathing difficulties. Thromplat 50mg Tablet is contraindicated in patients with severe liver impairment or active liver disease. It may cause liver toxicity, which can be identified through elevated liver enzymes and bilirubin levels. Therefore, extra caution is necessary in people with existing liver disorders, as the medicine may further affect liver function.

Your doctor may recommend regular eye examinations to monitor for cataracts. If you do not undergo routine eye check-ups, your doctor may schedule them during treatment. You may also be examined for bleeding in or around the retina, the light-sensitive tissue located at the back of the eye.

If you discontinue this tablet, your platelet count may decrease again within a few days. Your doctor will regularly monitor your platelet levels and advise you on the necessary precautions. While a very high platelet count can increase the risk of blood clots, clotting may also occur even when platelet levels are normal or low. Your doctor will adjust the dosage of this medicine to help maintain a safe platelet count.

Avoid taking this tablet with milk or other dairy products because the calcium they contain can reduce the absorption of the medicine. Use reliable contraception while receiving treatment, and inform your doctor immediately if you become pregnant. Thromplat 50mg Tablet is not recommended for children below one year of age with ITP. It is also not advised for patients younger than 18 years with low platelet counts caused by hepatitis C infection or severe aplastic anaemia.

Inform your doctor about all medicines you are taking, have recently taken, or plan to take. This includes prescription medicines, over-the-counter products, and vitamin supplements.

Uses

Thromplat 50mg Tablet is used to treat, Low platelet counts are caused by primary immune thrombocytopenia (ITP) or hepatitis C virus (HCV) infection. Severe aplastic anemia.

How it works

Thromplat 50mg Tablet stimulates megakaryocytes (the large bone marrow cells) responsible for producing platelets. By raising the number of platelets in the blood, this drug prevents bleeding and bruising.

How to Use

It is an orally available prescription drug. Your doctor will decide the dose and duration of the drug based on the disease condition and other factors. Always take an Thromplat 50mg Tablet as prescribed by your doctor. Take the tablet with or without food. Do not chew, crush, or break the tablet. Swallow the whole tablet with water.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Common Nausea Diarrhea, abdominal pain Common cold Cough Respiratory tract infection Back pain High temperature, cough Loss of appetite Hair loss Swelling in feet or hands Headache, dizziness Mouth and throat pain Joint pain

Expert Tips

Ensure that in the 2 hours after or 4 hours before you take this medication, you don’t consume dairy foods (such as cheese or butter), milk or milkshakes, antacids, and supplements containing iron, aluminum, magnesium, calcium, selenium, zinc, or calcium. If you forget to take Thromplat 50mg Tablet, take your next dose at the usual time. Do not take more than one dose of this drug daily. Don’t stop taking this tablet without talking to your doctor. If your doctor advises you to stop treatment, your platelet count will be checked each week for four weeks. If you have any doubts regarding the use of this medicine, ask your doctor.

References

  1. Novartis Pharmaceuticals UK Limited, Electronic medicines compendium (EMC), [ Revised on Jan 2022] [Accessed on 22 May 2023], https://www.medicines.org.uk/emc/files/pil.508.pdf
  2. GlaxoSmithKline, US Food and Drug Administration, [ Revised on October 2008] [Accessed on 22 May 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2008/022291lbl.pdf
  3. Revolade, Annex I summary of Product Characteristics - European Medicines Agency. Available at: https://www.ema.europa.eu/en/documents/product-information/revolade-epar-product-information_en.pdf [Accessed on 22 May 2023].

Safety Advice

Pregnancy: unsafe Thromplat 50mg Tablet is not recommended for pregnant patients because it may cause fetal harm. You must inform your doctor if you are pregnant, suspecting, or planning to get pregnant during the treatment.

Lungs: Consult your doctor It is unknown whether Thromplat 50mg Tablet can be prescribed for patients with lung problems. Consult your doctor if you have any lung diseases before starting the treatment.

Breastfeeding: Consult your doctor It is not known whether Thromplat 50mg Tablet passes into breast milk. If you are breastfeeding or planning to breastfeed, tell your doctor.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS