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Ticastro AS Combikit Tablet

Salt Composition: TICAGRELOR,ASPIRIN

₹243.00₹304.22

Inclusive of all taxes

Categories: Cardiology

Conditions: Heart Disorder

Product Introduction

Ticastro-AS Combikit Tablet is a combination medicine containing Ticagrelor and Aspirin, formulated to provide dual antiplatelet protection against heart attacks and strokes. This combination is commonly prescribed to help manage cardiovascular conditions in patients who have a high risk of developing blood clots, including those with acute coronary syndrome (ACS) or individuals who have undergone coronary procedures such as stent placement. Ticagrelor is a P2Y12 receptor inhibitor that prevents platelets from clumping together, thereby lowering the risk of clot formation. Aspirin, an established anti-inflammatory and antiplatelet medicine, enhances this effect by blocking the production of thromboxane A2, a substance that promotes platelet aggregation. Together, these two medicines work synergistically to reduce the risk of serious cardiovascular complications, including heart attacks, strokes, and stent-related clotting or repeat revascularization procedures.

Uses

Prevention of heart attack and stroke Acute coronary syndrome (ACS) Post-percutaneous coronary intervention (PCI) therapy Prevention of thrombotic cardiovascular events

How it works

1. Acute Coronary Syndrome (ACS) : Ticastro-AS Combikit Tablet is commonly prescribed for patients with acute coronary syndrome, including those experiencing unstable angina or non-ST elevation myocardial infarction (NSTEMI). The combination of Ticagrelor and Aspirin helps reduce the risk of further clot formation, thereby preventing heart attacks, strokes, or other serious cardiovascular events. 2. Post-Myocardial Infarction (Heart Attack) : Following a heart attack, this medication is used to prevent the recurrence of thrombotic events. Ticagrelor inhibits platelet aggregation, and Aspirin prevents the formation of thromboxane A2, further reducing the chances of another heart attack or stroke.

How to Use

Ticastro-AS Combikit Tablet should be taken exactly as prescribed by your healthcare provider. It is typically consumed orally, with or without food, to suit your preference. Swallow the tablet whole with a glass of water—do not crush, break, or chew it, as this may affect its effectiveness.

Side Effects

Like any medication, Ticastro-AS Combikit Tablet may cause side effects, though not everyone will experience them. It’s important to be aware of these potential effects and consult your healthcare provider if any of them occur. Common Side Effects: Bleeding (e.g., nosebleeds, bleeding gums, easy bruising) Headache Dizziness or lightheadedness Gastrointestinal discomfort (e.g., nausea, indigestion, heartburn) Shortness of breath or difficulty breathing Fatigue or tiredness Serious Side Effects: Severe bleeding (e.g., in the brain or stomach) Black or bloody stools Coughing up blood Severe allergic reactions (e.g., rash, itching, swelling of the face or throat) Liver problems (e.g., yellowing of the skin or eyes, dark urine)

Expert Tips

While Ticastro-AS Combikit Tablet can be highly effective in managing cardiovascular conditions, it’s essential to follow your healthcare provider's instructions closely. Always take the medication as prescribed, and do not stop or adjust the dosage without consulting your doctor, even if you feel better. Given the potential for bleeding risks, it’s important to report any unusual symptoms, such as bruising, bleeding, or shortness of breath, to your healthcare provider immediately. Regular check-ups, including blood tests and monitoring for signs of bleeding, are essential to ensure the medication is working safely and effectively.

References

  1. https://www.nejm.org/doi/full/10.1056/NEJMoa1908419
  2. https://www.nhs.uk/medicines/ticagrelor/

Safety Advice

Pregnancy: Consult your doctor Ticastro-AS Combikit Tablet is classified as Category C during pregnancy. There is limited data on its safety, so it should only be used if the potential benefits outweigh the risks. It’s important to consult your doctor before taking this medication if you are pregnant or planning to become pregnant.

Lungs: unsafe Patients with severe lung issues should use Ticastro-AS Combikit Tablet cautiously, as both components may affect kidney function. Kidney function should be monitored closely during treatment.

Breastfeeding: unsafe Both Ticagrelor and Aspirin pass into breast milk, although the effects on a nursing infant are not fully known. It is generally advised to avoid the use of Ticastro-AS Combikit Tablet while breastfeeding unless absolutely necessary. Consult your healthcare provider to assess the risks and determine the most appropriate treatment option.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS