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Tiloshil 100mg Capsule
Salt Composition: TEMOZOLOMIDE
- Manufacturer: SHILPA MEDICARE LTD
- Pack Size: 5 CAPSULE(s) IN A BOTTLE
- Dosage Form: CAPSULE
- Strength: 100MG
- Prescription Required
- Storage: Keep tiloshil 100mg capsule out of sight and reach of children. Store protected from light and moisture. Do not store above 25°C.
₹1060.00₹7059.00
Inclusive of all taxes
Product Introduction
Tiloshil 100mg capsule contains the active ingredient Temozolomide. It is an antitumor agent indicated for treating brain cancers including glioblastoma multiforme in adults and malignant glioma, including glioblastoma multiforme or anaplastic astrocytoma in patients older than three years. Glioblastoma and anaplastic astrocytoma are among the most common and aggressive brain cancers associated with low survival rates. Anaplastic astrocytoma is treated with Tiloshil 100mg capsule or radiotherapy following biopsy. Glioblastoma multiforme is treated with a combination of radiotherapy and Tiloshil 100mg capsule, continued as maintenance therapy.
Common side effects associated with Tiloshil 100mg capsule include nausea, vomiting, dizziness, diarrhoea, constipation, hair loss, rashes, tiredness, frequent urination, vision and hearing problems, elevated blood sugar levels, muscle damage, pain in muscles and joints, memory loss, coordination problems, infections, sleep disturbances and weight loss. Inform your doctor if any of these symptoms occur or persist. Notify your physician if you are allergic to Tiloshil 100mg capsule or any of its ingredients.
Before starting treatment with this medication, inform your physician if you have hepatitis B infection, anaemia, low platelet count, low levels of RBC and WBC, blood clotting problems, or any liver or kidney problems. Your physician will monitor your WBC and platelet counts regularly. Avoid this medication if you are pregnant or breastfeeding. Both women and men should use contraception to avoid pregnancy and fathering a child.
Uses
Treatment of newly diagnosed glioblastoma multiforme. Treatment of refractory anaplastic astrocytoma.
How it works
Tiloshil 100mg capsule acts by inhibiting the production of genetic material (DNA and RNA) of the cancer cells, which results in preventing their cell growth and multiplication, thereby preventing cancer spread to other parts of the body.
How to Use
This medicine is given only in a hospital setup by a healthcare provider. Tiloshil 100mg capsule will be given to you by your doctor. It is given intravenously (into a vein). Your physician will decide the dosage and frequency of this injection based on the severity of your disease and other factors.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious Secondary cancer like myelodysplastic syndrome and myeloid leukemia. Severe Allergic reactions Inflammation and fluid buildup in lungs Blood clot in lungs or legs Liver toxicity Convulsions Fever and chills Severe headache Uncontrolled bleeding Common Hair loss Rashes Tiredness Nausea, vomiting and diarrhea Constipation High blood sugar levels Dizziness, impaired sensation, tingling sensation, abnormal taste Vision and Hearing problem Frequent urination Muscle damage, pain in muscles and joints Weight changes Infections and wounds Amnesia Abnormal blood cell counts Loss of appetite Sleep problems Memory loss Difficulty concentrating, changes in mental status and alertness Coordination problems
Expert Tips
It is advised to use effective birth control for both men and women taking tiloshil 100mg capsule. Women of reproductive potential must use effective contraception during and after six months of therapy. Male patients receiving tiloshil 100mg capsule treatment should refrain from fathering children and should use reliable contraception during and for three months following the treatment. Your doctor could suggest routine blood tests to check your electrolyte levels, blood cell count, and liver function.
References
- Sun Pharmaceutical Industries, Electronic Medicines Compendium (EMC) [Revised on Feb 2022] [Accessed on 21 Nov 2022] https://www.medicines.org.uk/emc/files/pil.5318.pdf
- Pfizer, US Food and Drug Administration, [Revised on Sep 2015] [Accessed on 21 Nov 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/021029s031lbl.pdf
- Neha Singh et al., Mechanisms of temozolomide resistance in glioblastoma - a comprehensive review, Cancer Drug Resist; Published on Mar 2021; Accessed on 21/09/2022; https://cdrjournal.com/article/view/3779
- Zerong Tian et al., Glioblastoma and Anaplastic Astrocytoma: Differentiation Using MRI Texture Analysis, Front. Oncol., Published on Sep 2019; Accessed on 21/09/2022; https://www.frontiersin.org/articles/10.3389/fonc.2019.00876/full
Safety Advice
Pregnancy: unsafe Tiloshil 100mg capsule is unsafe to use during pregnancy as it may cause fetal harm. It should not be used unless prescribed by your physician. Women with childbearing potential should use effective contraceptive precautions for at least 6 months following the completion of treatment.
Lungs: Consult your doctor It is unknown whether tiloshil 100mg capsule can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.
Breastfeeding: unsafe Tiloshil 100mg capsule is unsafe to use during breastfeeding as it passes through breast milk and harm the baby. Consult your physician for advice before breastfeeding.
Disclaimer
The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.