Tishtha 40mg Injection

Tishtha 40mg Injection contains the active substance Nivolumab. It is indicated for the treatment of cancers of the skin, lungs, kidney, lymph nodes, bladder, oesophagus, and urinary tract. This medicine is indicated when cancer has recurred following treatment with medicines, surgery, and radiation. It is an immunotherapy medication that enhances the immune system's ability to fight cancer. It works by targeting and blocking specific molecules that suppress the immune system's capacity to recognise and attack cancer cells. By inhibiting these molecules, it strengthens the immune response against cancer and may reduce or slow tumour growth. A key advantage of this and other immunotherapy drugs is their potential to produce durable responses in some patients, even after treatment completion. This differs from traditional chemotherapy and radiation therapy, which typically offer temporary benefits and carry significant adverse effects. Tishtha is contraindicated in patients with severe hypersensitivity to the drug or its components. It is also contraindicated in patients with certain autoimmune disorders, including lupus and rheumatoid arthritis, because the drug can further stimulate the immune system and worsen these conditions. Additionally, caution should be exercised in patients with a history of organ transplantation.

Advanced skin cancer (melanoma) Skin cancer that recurs after surgery Advanced non-small cell lung cancer Advanced kidney cancer Hodgkin’s lymphoma (lymph node disease) Advanced cancer of the head and neck Advanced urinary tract and bladder cancer Advanced oesophageal cancer

The therapeutic effect of Tishtha 40mg Injection is to enhance the body's natural immune response to cancer cells. Cancer cells can often evade the immune system by producing proteins that bind to immune cells and prevent them from recognizing and attacking the cancer cells. It works by blocking the interaction between a protein called programmed death-1 (PD-1), found on the surface of immune cells, and its corresponding ligands. Doing so enables the immune system to recognize and attack cancer cells more effectively, helping to slow down or even stop cancer progression. In some cases, treatment with it can lead to long-lasting remission, even after treatment has ended. This is because the drug can stimulate the immune system to "remember" the cancer cells and continue to attack them even after the drug has been cleared from the body.

Tishtha 40mg Injection is a medication a healthcare professional administers, typically in a hospital or clinic setting. The medication is given as an intravenous (IV) infusion by healthcare professional. The infusion typically takes several hours. You will be closely monitored during and after the infusion to ensure the medication works effectively and to watch for any side effects. The dosage and frequency of administration will depend on the condition being treated and your circumstances. Your healthcare provider will determine the appropriate dosage and schedule for you.

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious: Pneumonitis (inflammation of lung tissue) Colitis (inflammation of the colon) Hepatitis (inflammation of the liver) Hypothyroidism Hyperthyroidism Adrenal insufficiency (a condition in which the adrenal glands do not produce enough hormones). Severe allergic reactions Infusion-related reactions Confusion Seizures Neuropathy Eye disorders (such as uveitis or iritis) Common: Fatigue Nausea Skin rash Itching Loss of appetite Diarrhea Constipation Joint pain Headache

Discuss the potential risks and benefits of Tishtha 40mg Injection with your healthcare provider before or during treatment. Follow all safety precautions and guidelines given by your healthcare provider to reduce possible risks. Report any new or worsening symptoms to your healthcare provider immediately, as some side effects may be serious. Women of reproductive age should use effective contraception during treatment and for at least 5 months after the last dose to prevent harm to a developing fetus. Take care of your overall health during treatment. Eat a balanced diet, get enough rest, and seek support from family, friends, or support groups.