Tocira 400mg Injection

Tocira 400mg injection contains tocilizumab, a monoclonal antibody (a protein derived from specific immune cells). It is indicated in moderate to severe active rheumatoid arthritis (RA) in patients with inadequate response to other rheumatoid medicines, giant cell arteritis (arterial inflammation), systemic juvenile idiopathic arthritis (sJIA) in children, and polyarticular juvenile idiopathic arthritis (pJIA) in children aged 1 to 2 years and above, where it reduces joint pain and swelling.

Children with allergies to any ingredient and those with severe infections require medical evaluation before initiating treatment. Immediate medical attention is necessary if patients develop allergic reactions (breathing difficulty, chest tightness, rash, itching, hives, swelling of lips, tongue, or face), infection (short- or long-term), tuberculosis, intestinal ulcers or diverticulitis (small bulging pouches in the digestive tract), liver disease, cancer, kidney function impairment, or persistent headaches. Patients with a history of macrophage activation syndrome (activation and uncontrolled proliferation of specific blood cells) require medical notification. Elderly patients carry increased infection risk compared to the general population and warrant careful clinical consideration. Medical consultation is necessary for patients planning pregnancy, those who may be pregnant, or those who are breastfeeding.

Rheumatoid arthritis Giant cell arteritis (GCA) Polyarticular Juvenile Idiopathic Arthritis (pJIA) Systemic Juvenile Idiopathic Arthritis (sJIA) Cytokine release syndrome

Tocira 400mg injection inhibits the function of a particular protein known as interleukin-6, which plays a role in the body's inflammatory responses. By blocking this protein, it can help decrease inflammation within your body.

Tocira 400mg injection will be administered to you by a healthcare professional in a hospital setting. It is usually administered in the vein (intravenous). Your doctor will decide the dose, route of administration, and frequency based on your disease condition and other factors.

Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them. Serious Allergic reaction (difficulty with breathing, chest tightness, rash, itching, hives, swelling in the lips, tongue, or face) Fever and chills Mouth or skin blisters Stomach ache Common Upper respiratory tract infections (cough, blocked nose, runny nose, sore throat and headache) High blood fat (cholesterol) levels Injection site reactions. Lung infection (pneumonia) Shingles (herpes zoster) Cold sores (oral herpes simplex), blisters Eye infection (conjunctivitis) Headache, dizziness, high blood pressure Mouth ulceration, stomach pain Fluid retention (edema) in the lower legs, weight increase Cough, shortness of breath Low white blood cell counts (neutropenia, leucopenia) Abnormal liver function tests (increased transaminases) Increased bilirubin shown by blood tests Low fibrinogen levels in the blood (a protein involved in blood clotting)

Talk to your doctor if you have recently been vaccinated or are planning a vaccination because a certain vaccination (Live vaccine) should not be given while taking tocira 400mg injection. Your doctor will advise you to check the blood if you have low white blood cells, platelets, or elevated liver enzymes before giving you the medicine.