Home › Products › Nephrology › Toromus 0.5mg capsule

Toromus 0.5mg capsule

Salt Composition: TACROLIMUS

₹194.00₹215.62

Inclusive of all taxes

Toromus 0.5mg capsule

Categories: Nephrology

Conditions: Transplant

Product Introduction

Toromus 0.5mg capsule contains the active substance Tacrolimus. It is an immunosuppressant that belongs to the class of medications called calcineurin inhibitors. Tacrolimus is used along with other medicines to prevent organ transplant rejection in patients receiving liver, kidney, heart, or other transplants. It is also indicated to control the body's immune response, enabling it to accept the transplanted organ. Do not take Toromus 0.5mg capsule if you are allergic to tacrolimus or any of the other ingredients of this medicine. Report to your physician if you are allergic to any antibiotic group. Inform your doctor if you have had a liver or heart disease before initiating treatment. Notify your physician immediately if you develop fever, bruising under the skin (which may appear as red dots), unexplained tiredness, confusion, yellowing of the skin or eyes, reduced urine output, vision loss, and seizures after taking this medicine. Limit exposure to sunlight and UV light while consuming tacrolimus by wearing appropriate protective clothing and sunscreen with a high sun protection factor. This medicine may cause skin changes with immunosuppressive therapy. This medicine may cause diarrhoea; inform your physician if you have diarrhoea for over a day. If you need to receive any vaccinations, consult your doctor before accepting them.

Uses

Toromus 0.5mg capsule uses are: Prevent organ transplant rejections.

How it works

Tacmod Ointment 10gm provides immunosuppression by inhibiting T-lymphocyte activation and proliferation and T-helper-cell-dependent B-cell response. It works by attaching to a protein called FKBP-12 and forms a complex called tacrolimus-FKBP, which inhibits the action of calcineurin phosphatase. This, in turn, inhibits the formation of T cells and suppresses the immune response.

Side Effects

Toromus 0.5mg side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Common Swelling in the arm or leg Hair loss Itchy skin Constipation, diarrhoea Nausea, vomiting Anemia Headache Cough Serious Increased or decreased heartbeats GI bleeding Liver Injury Seizure Acute kidney failure Lung infection or respiratory problems

References

  1. Prograf 0.5mg Hard Ointments - Summary of Product Characteristics (SmPC) - (emc). www.medicines.org.uk. Published December 2022. Accessed May 25, 2023. https://www.medicines.org.uk/emc/product/6720/smpc
  2. Highlights Of Prescribing Information, Prograf ® (Tacrolimus) Ointments PROGRAF ® (Tacrolimus) Injection, (for Intravenous Use).; Revised 2012. Accessed May 25, 2023. https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/050709s031lbl.pdf
  3. Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Immunosuppressants, tolerogens, and immunostimulants, 12th edition, 2011, 1008.
  4. KD Tripathi, Essentials of Medical Pharmacology, Immunosuppressant drugs, 7th edition, 2013, 881.

Safety Advice

Pregnancy: Unsafe Based on animal studies, Toromus 0.5mg capsule can cause harmful effects on the baby. Inform your physician if you are pregnant, suspecting pregnancy or planning to get pregnant before initiating the treatment.

Lungs: Consult Your Doctor It is unknown whether Toromus 0.5mg capsule can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.

Breastfeeding: Unsafe Do not consume Toromus 0.5mg capsule if you are breastfeeding because this medicine is excreted into breast milk and may cause harmful effects on the body.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS