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Trabec 1mg Infusion
Salt Composition: TRABECTEDIN
- Manufacturer: NATCO PHARMA LTD
- Pack Size: 1 VIAL(s)
- Dosage Form: INFUSION
- Strength: 1MG
- Prescription Required
- Cold Chain
- Prepaid Only. Non-Returnable.
- Storage: Store Trabec 1MG Infusion in the refrigerator (2°C to 8°C) Do not freeze keep the injection away from the reach of children and pets. If you have missed any dosing appointments, inform your doctor and schedule immediately.
₹21450.00₹26812.50
Inclusive of all taxes
Product Introduction
Trabec 1mg Infusion contains Trabectedin, an antineoplastic agent belonging to the alkylating agents class. It is indicated for treatment of liposarcoma (cancer arising in fat cells) or leiomyosarcoma (cancer arising in smooth muscle tissue) that has metastasised to other body sites and cannot be managed surgically in patients who have received prior anti-cancer therapy. It is also indicated for recurrent ovarian cancer following at least one previous treatment line in patients who have not responded to other therapies.
Do not take Trabec 1mg Infusion if you are allergic to Trabectedin or any other ingredient in this medicine, if you have serious infections, if you are breastfeeding, or if you will receive a yellow fever vaccine. Inform your doctor if you have an active infection, or history of infections, liver disease, kidney problems, or cardiac disease. This medicine may impair fertility; discuss with your doctor before planning pregnancy. Report to your doctor if you experience sudden difficulty in breathing, fever, skin redness or flushing, rash, nausea, or vomiting following the infusion. Trabec 1mg Infusion is not recommended in children and young people under 18 years of age. Use effective contraception during treatment. Avoid pregnancy and breastfeeding during therapy.
Uses
Liposarcoma or Leiomyosarcoma
How it works
Trabec 1MG Infusion is an alkylating agent, that causes a disruption in the tumor cell cycle and cell death by initiating a cascade of events triggered by the binding of certain nucleobases in the DNA preventing the multiplication of tumor cells. It works by slowing or stopping the growth of cancer cells in the body
How to Use
It will be given to you by a doctor or nurse in a hospital or clinic setting trained in cancer chemotherapy. It is given as an intravenous infusion drip (into your vein). Do not self-administer the injection. Your doctor will decide the dose and duration of the treatment based on your disease severity, body weight, and other factors. Your doctor will give you certain medications to lessen the chance of getting side effects from the Trabec 1MG Infusion treatment.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Common Constipation Decrease in appetite Diarrhea Nausea, vomiting Anemia Decreased albumin levels Decreased platelet count Headache Shortness of breath Tiredness Serious Heart problems Skin rashes Liver problems Severe muscle pain
Expert Tips
Trabec 1MG Infusion may interfere with vaccines, inform your physician before taking yellow fever vaccine or any other vaccines. This injection may cause severe birth defects if taken during pregnancy. Female patients with reproductive potential should use effective contraception during the treatment. Male patients with female partners with reproductive potential should use effective birth control methods during the treatment and for at least 5 months after their last dose. Do not breastfeed during treatment with this injection. Your doctor may advise you to take certain tests to check for the effectiveness of the therapy.
References
- Yondelis 0.25 mg powder for concentrate for solution for infusion - Summary of Product Characteristics (SmPC) - (emc). www.medicines.org.uk. Revised 2022. Accessed April 28, 2023. https://www.medicines.org.uk/emc/product/6164/smpc
- Yondelis - Trabec 1MG Infusion .; Revised on 2018. Accessed April 28, 2023. https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/207953s005lbl.pdf
- Demetri et al., Efficacy and Safety of Trabec 1MG Infusion or Dacarbazine for Metastatic Liposarcoma or Leiomyosarcoma After Failure of Conventional Chemotherapy: Results of a Phase III Randomized Multicenter Clinical Trial, Journal of Clinical Oncology, 2016, 34(8), [ Accessed April 28, 2023], https://ascopubs.org/doi/pdfdirect/10.1200/jco.2015.62.4734
Safety Advice
Pregnancy: unsafe Trabec 1MG Infusion is unsafe to administer in pregnant women because it may affect the fetus. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant. Using an effective birth control method during the treatment and for 3 months after your last dose is necessary.
Lungs: Consult your doctor It is unknown whether Trabec 1MG Infusion can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.
Breastfeeding: unsafe Breastfeeding is not recommended in patients taking Trabec 1MG Infusion because the medicine passes into the breast milk in small amounts and may harm your baby.
Disclaimer
The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.