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Tremfya 100mg Injection
Salt Composition: GUSELKUMAB
- Manufacturer: JOHNSON & JOHNSON PVT LTD
- Pack Size: 1 PREFILLED SYRINGE(s)
- Dosage Form: PREFILLED SYRINGE
- Strength: 100MG
- Prescription Required
- Cold Chain
- Prepaid Only. Non-Returnable.
- Storage: Storage: Store the Tremfya 100 mg mL syringe in the refrigerator (2°C–8°C). Do not freeze. Protect from direct light. Do not shake. Use each prefilled syringe only once.
₹103125.00₹110743.12
Inclusive of all taxes
Product Introduction
Tremfya 100mg Injection contains guselkumab, a human monoclonal antibody indicated for chronic inflammatory disorders, including moderate to severe plaque psoriasis and active psoriatic arthritis. It is a member of the interleukin-23 (IL-23) inhibitor class, which reduces inflammation arising from immune system dysfunction. Tremfya 100mg Injection is prescribed for adults eligible for systemic therapy or phototherapy. The medicine works by selectively inhibiting IL-23, a cytokine implicated in the pathological immune activity underlying psoriasis and psoriatic arthritis, thereby improving cutaneous manifestations and reducing joint-based inflammation. Commonly reported adverse effects include upper respiratory tract infections, headaches, fatigue, arthralgias, diarrhoea, and injection site reactions. Patients should seek immediate medical attention if they develop signs of serious allergic reaction, infection, or respiratory distress.
Uses
Moderate to severe plaque psoriasis in adults who are candidates for systemic treatment or phototherapy Active psoriatic arthritis in adults, either alone or in combination with other disease-modifying antirheumatic drugs (DMARDs)
How it works
Tremfya subcutaneous injection binds specifically to the p19 subunit of interleukin-23 (IL-23), preventing it from activating inflammatory pathways. By blocking this protein, the Tremfya 100 mg ml injector reduces skin plaques and joint pain, offering long-term control of chronic inflammatory diseases. It helps lower immune system overactivity without broadly suppressing immunity.
Side Effects
Common Side Effects: Upper respiratory infections (cold, sore throat) Headache Diarrhea Joint pain Redness or pain at the injection site Serious Side Effects: Serious allergic reactions (rash, swelling, difficulty breathing) Increased risk of infections such as tuberculosis (TB) Liver enzyme abnormalities Reactivation of latent infections (like hepatitis B) Contact your doctor immediately if you experience persistent fever, chills, cough, or shortness of breath.
Expert Tips
Before starting Tremfya 100mg Injection, your doctor may test for latent tuberculosis. Do not stop or skip doses unless directed by your healthcare provider. Avoid live vaccines and limit exposure to people with contagious infections. Maintain a skincare routine and apply sunscreen regularly, as some patients may experience increased skin sensitivity. Never share your prefilled injection with others.
References
- https://reference.medscape.com/drug/tremfya-guselkumab-1000164
- https://go.drugbank.com/drugs/DB11834
- https://www.ema.europa.eu/en/documents/product-information/tremfya-epar-product-information_en.pdf
- https://www.jnj.com/media-center/press-releases/tremfya-guselkumab-receives-u-s-fda-approval-for-adults-with-moderately-to-severely-active-ulcerative-colitis-strengthening-johnson-johnsons-leadership-in-inflammatory-bowel-disease
Safety Advice
Pregnancy: Consult Your Doctor Use with caution. Limited data is available on Tremfya 100mg Injection use during pregnancy. Consult your doctor if you are pregnant or planning to conceive.
Lungs: Consult Your Doctor Inform your doctor if you have a history of tuberculosis (TB) or chronic lung disease before starting treatment.
Breastfeeding: Consult Your Doctor The safety of Tremfya 100mg Injection during breastfeeding is not fully established. Use only when absolutely necessary, and only under medical supervision.
Disclaimer
The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.