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Trombopag 25mg Tablet

Salt Composition: ELTROMBOPAG

₹1435.00₹1687.50

Inclusive of all taxes

Trombopag 25mg Tablet

Categories: Infectious Disease

Conditions: Anticoagulants

Product Introduction

Trombopag 25mg tablet is a thrombopoietin (TPO) receptor agonist containing the active ingredient Eltrombopag. It is indicated for treating low platelet counts caused by primary immune thrombocytopenia (ITP) or hepatitis C (HCV) infection. ITP is an autoimmune disorder in which the immune system destroys platelets. Platelets are blood cells essential for clotting and maintaining blood vessel wall integrity. Low platelet levels can result in severe bleeding and bruising. This tablet is also used in adults to treat low blood counts caused by severe aplastic anaemia, a serious blood disease occurring when the bone marrow fails to produce sufficient new blood cells.

This drug is contraindicated in individuals with known hypersensitivity or allergic reactions to Eltrombopag or its components. Allergic reactions may range from mild to severe and include symptoms such as rash, itching, swelling, dizziness, or difficulty breathing. Trombopag 25mg tablets are contraindicated in patients with severe liver impairment or active liver disease. The drug can cause hepatotoxicity, as evidenced by increased liver enzymes and bilirubin levels. Use in individuals with severe liver disease may further worsen liver function, and caution is advised.

Your doctor will recommend screening for cataracts. Regular eye testing should be arranged if you do not have routine eye examinations. You may also be assessed for bleeding in or around your retina, the light-sensitive layer of cells at the back of the eye. Upon stopping this tablet, your blood platelet count is likely to decrease within several days. Platelet count will be monitored, and your doctor will discuss appropriate precautions. A very high blood platelet count may increase the risk of blood clotting. However, blood clots can form with normal or even low platelet counts. Your doctor will adjust your dose to ensure your platelet count does not become excessively high.

Do not take this tablet with dairy products or drinks, as calcium affects the medicine's absorption. Use effective contraception during treatment. If you become pregnant, inform your doctor immediately. Trombopag 25mg tablets are not advised for children under one year with ITP. It is not recommended for patients under 18 years with low platelet counts caused by hepatitis C or severe aplastic anaemia. Inform your doctor of all medicines you are taking, have recently taken, or might take, including over-the-counter medicines and vitamins.

Uses

Trombopag 25mg tablet is used to treat: Low platelet counts are caused by primary immune thrombocytopenia (ITP) or hepatitis C virus (HCV) infection. Severe aplastic anemia.

How it works

Trombopag 25mg tablet stimulates megakaryocytes (the large bone marrow cells) responsible for producing platelets. By raising the number of platelets in the blood, this drug prevents bleeding and bruising.

How to Use

It is an orally available prescription drug. Your doctor will decide the dose and duration of the drug based on the disease condition and other factors. Always take an Trombopag 25mg tablet as prescribed by your doctor. Take the tablet with or without food. Do not chew, crush, or break the tablet. Swallow the whole tablet with water.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Common: Nausea Diarrhea, abdominal pain Common cold Cough Respiratory tract infection Back pain High temperature, cough Loss of appetite Hair loss Swelling in feet or hands Headache, dizziness Mouth and throat pain Joint pain

Expert Tips

Ensure that in the 2 hours after or 4 hours before you take this medication, you don’t consume dairy foods (such as cheese or butter), milk or milkshakes, antacids, and supplements containing iron, aluminum, magnesium, calcium, selenium, zinc, or calcium. If you forget to take the Trombopag 25mg tablet, take your next dose at the usual time. Do not take more than one dose of this drug daily. Don’t stop taking this tablet without talking to your doctor. If your doctor advises you to stop treatment, your platelet count will be checked each week for four weeks. If you have any doubts regarding the use of this medicine, ask your doctor.

References

  1. Novartis Pharmaceuticals UK Limited, Electronic medicines compendium (EMC), [ Revised on Jan 2022] [Accessed on 22 May 2023], https://www.medicines.org.uk/emc/files/pil.508.pdf
  2. GlaxoSmithKline, US Food and Drug Administration, [ Revised on October 2008] [Accessed on 22 May 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2008/022291lbl.pdf
  3. Revolade, Annex I summary of Product Characteristics - European Medicines Agency. Available at: https://www.ema.europa.eu/en/documents/product-information/revolade-epar-product-information_en.pdf [Accessed on 22 May 2023].

Safety Advice

Pregnancy: unsafe Trombopag 25mg tablet is not recommended for pregnant patients because it may cause fetal harm. You must inform your doctor if you are pregnant, suspecting, or planning to get pregnant during the treatment.

Lungs: Consult your doctor It is unknown whether Trombopag 25mg tablet can be prescribed for patients with lung problems. Consult your doctor if you have any lung diseases before starting the treatment.

Breastfeeding: Consult your doctor It is not known whether Trombopag 25mg tablet passes into breast milk. If you are breastfeeding or planning to breastfeed, tell your doctor.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS