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Tucaone 150mg Tablet

Salt Composition: TUCATINIB

₹6297.00₹7678.13

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Tucaone 150mg Tablet

Categories: Oncology

Conditions: Anti Cancer

Product Introduction

Tucaone 150mg Tablet is indicated for the treatment of HER2-positive breast cancer, particularly in patients with metastatic disease including brain metastases. It is administered in combination with trastuzumab and capecitabine. Tucatinib, the active ingredient in Tucaone 150mg Tablet, functions as a HER2 protein inhibitor, reducing proliferation and spread of cancer cells. Tucatinib is a targeted therapy rather than a cytotoxic chemotherapy agent, offering selectivity towards cancer cells with reduced impact on healthy tissue. Treatment requires physician supervision and ongoing monitoring to assess efficacy and safety.

Uses

Tucaone 150mg Tablet is used for: HER2-positive advanced or metastatic breast cancer Brain metastases in HER2+ breast cancer patients Use in combination with trastuzumab and capecitabine after previous HER2-directed therapies This therapy is typically considered when other standard HER2 treatments have become ineffective.

How it works

Tucaone 150mg Tablet belongs to a group of medicines known as tyrosine kinase inhibitors (TKIs). It works by: Specifically targeting the HER2 receptor, a protein that promotes cancer cell growth Blocking HER2-related signalling pathways that drive tumour progression Working synergistically with other anticancer drugs like trastuzumab and capecitabine Crossing the blood-brain barrier to treat cancer that has spread to the brain This focused mechanism helps slow disease progression while minimising impact on normal cells.

Side Effects

Common Side Effects Some people may have: Loose motion (diarrhea) Feeling very tired Nausea or vomiting Mouth sores Less hunger Red or sore hands and feet Liver test changes (seen in blood reports) These usually go away with time or treatment. Tell your doctor if any feel too strong or last long. Serious Side Effects (Call Your Doctor Right Away) Yellow skin or eyes (could mean a liver problem) Bad diarrhea with weakness Trouble breathing or swelling (could be an allergy) High fever or infections Report any unexpected or persistent side effects to your doctor immediately.

References

  1. https://www.ncbi.nlm.nih.gov/books/NBK595112/
  2. https://www.nejm.org/doi/full/10.1056/NEJMoa1914609
  3. https://pubchem.ncbi.nlm.nih.gov/compound/Tucatinib

Safety Advice

Pregnancy: Unsafe Not recommended during pregnancy. Use effective contraception during and for at least 1 week after the last dose.

Lungs: Consult Your Doctor It is not known whether it affects lung function or not. Kindly consult your doctor if you have any lung infection or other problems

Breastfeeding: Unsafe Not recommended during breastfeeding. Use effective contraception during and for at least 1 week after the last dose.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS