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Twinrab 600IU Injection
Salt Composition: DOCARAVIMAB,MIROMAVIMAB
- Manufacturer: ZYDUS CADILA
- Pack Size: 1 VIAL(s) OF 1ML
- Dosage Form: INJECTION
- Strength: 600IU
- Prescription Required
- Cold Chain
- Prepaid Only. Non-Returnable.
- Storage: Keep docaravimab + miromavimab Injection out of sight and reach of children. Store between 2°C and 8°C.
₹1270.00₹1590.94
Inclusive of all taxes
Product Introduction
Twinrab 600IU injection is a combination medication containing docaravimab and miromavimab as active components belonging to the monoclonal antibodies group. It is indicated for post-exposure prophylaxis to prevent rabies infection in people exposed to the virus. It is administered in combination with the rabies vaccine. Rabies is a viral disease that causes inflammation of the brain and can spread to pets and people through bites or scratches from virus-carrying animals such as dogs and bats. Although rabies is a fatal disease, it is preventable. Before starting treatment, inform your healthcare professional of any known allergies to similar products. During and after treatment, monitor carefully for any adverse reactions. This injection is safe for use in children. Inform your doctor if you are pregnant or breastfeeding before receiving twinrab 600IU injection.
Uses
Prevent rabies infection
How it works
Twinrab 600IU injection contains two antibodies: docaravimab and miromavimab. These antibodies bind to the rabies virus and prevent it from entering and infecting nerve cells and other cells in the body. This interruption of the virus's ability to replicate and spread within the body is crucial for halting the progression of rabies infection.
How to Use
Twinrab 600IU injection is given only in a hospital set up by a trained healthcare provider. It will be given to you as an injection into your muscle (intramuscularly) for adults in the arm and children in the thigh. Your doctor will decide your most apt dosage based on age, body weight, and physical circumstances.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them. Serious Allergic Reactions Common Injection site pain Irritability Headache, dizziness Nausea
Expert Tips
For those prescribed twinrab 600IU injection, it is crucial to prioritize safety through open communication with your healthcare provider. Adhering strictly to the prescribed dosage and schedule is paramount. If this injection is combined with a rabies vaccine, ensure compliance with the recommended vaccination schedule. Attend all scheduled follow-up appointments for proper monitoring. Familiarize yourself with the signs of severe reactions and seek immediate medical attention if necessary. Communicate promptly with your healthcare provider regarding any changes in your health status. If you are pregnant or planning to breastfeed, discuss your plans with your healthcare provider. Always seek personalized advice from healthcare professionals to ensure your safety during treatment.
References
- Zydus; the U.S. Food And Drug Administration (FDA) [Accessed on 14/08/202] https://www.fda.gov/media/106517/download
- Kevinkumar Kansagra et al. A Phase 3, Randomised, Open-Label, Non-inferiority Trial Evaluating Anti-Rabies Monoclonal Antibody Cocktail (TwinrabTM) Against Human Rabies Immunoglobulin (HRIG); Clinical Infectious Diseases; Published on 17/06/2020; Accessed on 14/08/2021; https://pubmed.ncbi.nlm.nih.gov/32556113/
- De Melo GD et al., A combination of two human monoclonal antibodies cures symptomatic rabies; EMBO Mol Med; Published on 06/11/2020; Accessed on 13/11/2023 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7645379/
- Anti-rabies virus monoclonal antibodies, World Health Organisation (WHO), https://list.essentialmeds.org/recommendations/1220/print?format=pdf
Safety Advice
Pregnancy: Consult your doctor The safety and efficacy of this injection in pregnant women is not yet established. You need to tell your doctor if you are pregnant or planning to get pregnant before taking twinrab 600IU injection.
Lungs: Consult your doctor The safety and efficacy of this injection in lung patients have yet to be established. Inform your doctor if you have any lung disorder before taking twinrab 600IU injection.
Breastfeeding: Consult your doctor The safety and efficacy of this injection in breastfeeding women are not yet established. You need to inform your doctor if you are breastfeeding before taking twinrab 600IU injection.
Disclaimer
The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.