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Ujvira 100mg Injection

Salt Composition: TRASTUZUMAB EMTANSINE

₹20500.00₹37495.31

Inclusive of all taxes

Categories: Oncology

Conditions: Anti Cancer

Product Introduction

Ujvira 100mg Injection is a targeted anticancer therapy containing the active ingredient trastuzumab emtansine. The U.S. Food and Drug Administration (FDA) approved trastuzumab emtansine on February 22, 2013, for the treatment of HER2-positive metastatic breast cancer in patients who have previously received trastuzumab and chemotherapy. Ujvira 100mg Injection works by specifically targeting HER2-positive cancer cells, helping slow or stop their growth while minimizing damage to healthy cells. This medicine is not recommended for use in children and adolescents below 18 years of age, as its safety and effectiveness have not been established in this population. Before starting treatment with Ujvira 100mg Injection, inform your doctor if you have a history of blood clotting disorders, liver disease, or allergies to trastuzumab emtansine or any of its ingredients.

Uses

Ujvira 100mg Injection is indicated for its use in the following conditions: Advanced and metastatic breast cancer

How it works

Trastuzumab binds selectively to the HER2 receptors on breast cancer cells' surface, blocks them from receiving growth signals, and stops the cancer cell's growth. DM1 becomes active once the drug enters the cancer cells and helps stop cancer cell growth.

How to Use

Ujvira 100mg Injection shall either be administered before or after surgery. It will be given as an Intravenous infusion for 90 minutes, if well tolerated it shall be administered within 30 minutes for the next doses.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them. Serious Heart Problems Allergic reactions Kidney problems Breathing difficulties Common Fever Visual disturbances Nose bleeds or runny nose Hair loss Dizziness Nail disorders Weight loss Loss of appetite Bruising Dry mouth Liver inflammation Muscle pain Asthma/ lung disorders

Expert Tips

It is suggested to inform your doctor if you have a history of allergic reactions to Ujvira 100mg Injection to avoid life-threatening complications. If you have a history of lung disorder or breathing problems inform your doctor beforehand before the treatment commencement. Avoid planning for pregnancy and breastfeeding for a minimum of 7 months after the last dose. Monitor your heart parameters regularly during the treatment with Ujvira 100mg Injection as it may impact the functioning of heart.

References

  1. Roche, Electronic Medicines Compendium (EMC), [Revised on Jan 2022] [Accessed on 6th May 2023], https://www.medicines.org.uk/emc/files/pil.3856.pdf
  2. Genentech Inc, [Revised on Feb 2021] [Accessed on 6th May 2023], https://www.gene.com/download/pdf/herceptin_prescribing.pdf
  3. Anton Wellstein, Giuseppe Giaccone, Michael B. Atkins, and Edward A. Sausville, Pathway-Targeted Therapies: Monoclonal Antibodies, Protein Kinase Inhibitors, and Various Small Molecules, Goodman & Gilman’s Pharmacological Basis of Therapeutics, 13th Edition, 2018, 1203-1236

Safety Advice

Pregnancy: unsafe Discuss with your physician before taking this Ujvira 100mg Injection if you are pregnant or think you might be pregnant. Do not take this medicine during the pregnancy unless advised by the doctor to take as it may cause to the unborn baby.

Lungs: Consult your doctor Talk to your doctor if you have any lung conditions before starting treatment with Ujvira 100mg Injection.

Breastfeeding: unsafe Avoid breastfeeding your baby while on the treatment with Ujvira 100mg Injection atleast for at least seven months after the final dose.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS