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Ulinafic 1,00,000 IU Injection

Salt Composition: ULINASTATIN

₹1667.00₹3623.44

Inclusive of all taxes

Ulinafic 1,00,000 IU Injection

Categories: Others

Conditions: Others

Product Introduction

Ulinafic 1,00,000IU Injection contains the active ingredient ulinastatin, also referred to as a urinary trypsin inhibitor (UTI). It is a medication used in various countries for its anti-inflammatory and immunomodulatory effects. Originally isolated from human urine, ulinastatin has been researched for its potential therapeutic benefits in several inflammatory conditions. It is primarily used to treat acute pancreatitis, a condition marked by inflammation of the pancreas. This medicine is believed to work by blocking specific enzymes and inflammatory mediators, thereby reducing inflammation and decreasing the severity of the disease. Additionally, Ulinafic 1,00,000IU Injection has been studied for its possible role in treating conditions such as sepsis (a severe bacterial infection), multiple organ failure, and acute respiratory distress syndrome (ARDS). Its capacity to regulate the immune response and limit excessive inflammation makes it a potential treatment option for disorders where uncontrolled immune activity can lead to tissue damage. Ulinafic 1,00,000IU Injection may not be appropriate for all patients and is contraindicated in individuals with a known allergy or hypersensitivity to ulinastatin or any of its ingredients. Available evidence on the safety and effectiveness of this medicine in certain populations, including children and older adults, is limited. Therefore, it should be administered with caution and under the supervision of a healthcare professional in these groups. This medication may also interfere with certain laboratory tests and affect the accuracy of the results. Inform your doctor if you are receiving Ulinafic 1,00,000IU Injection before undergoing any diagnostic investigations. Do not discontinue treatment abruptly, especially in critically ill patients, as sudden withdrawal may result in adverse effects.

Uses

Ulinafic 1,00,000IU Injection is used to treat the following: Acute pancreatitis Sepsis Acute respiratory distress syndrome

How it works

Ulinafic 1,00,000IU Injection's mechanism of action involves inhibiting various proteolytic enzymes, such as trypsin and elastase, which are crucial in promoting inflammation and tissue damage. By suppressing these enzymes, this medication reduces the activation of inflammatory pathways and modulates the immune response, ultimately leading to decreased inflammation and potential mitigation of tissue injury.

How to Use

Ulinafic 1,00,000IU Injection is administered intravenously (vein injection) under medical supervision. Your healthcare professional will determine the specific dosage and administration guidelines based on your condition and needs.

Side Effects

Ulinafic 1,00,000IU Injection causes some side effects like all medications, although not everyone will experience them. Serious: Severe allergic reactions (difficulty breathing, swelling of the face or throat, hives, itching) Anaphylaxis (a life-threatening allergic reaction) Signs of an infection (fever, persistent sore throat) Changes in kidney function (changes in urine output, swelling of the legs or ankles) Abnormal bleeding or bruising Liver problems (yellowing of the skin or eyes, dark urine, abdominal pain) Neurological symptoms (confusion, seizures, difficulty speaking or moving) Common: Nausea Vomiting Diarrhea Skin rashes or itching Headache Dizziness Fever or chills Injection site reactions (pain, redness, or swelling)

Expert Tips

Patients with known hypersensitivity to Ulinafic 1,00,000IU Injection or any of its components should not use the medication. Regular monitoring of kidney and liver function is essential, and dose adjustments may be necessary for patients with impaired organ function. Caution is advised in pregnant and breastfeeding individuals, and the medication should only be used if needed and under medical supervision. Close monitoring for signs of allergic reactions, infections, and changes in blood counts is recommended. Patients with a history of gastrointestinal or bleeding disorders should be closely monitored during treatment. It's important to discuss all medical conditions and medications with the healthcare provider to ensure the safe and effective use of this medication.

References

  1. Bharat Serums and Vaccines Limited, [Accessed on 27th July 2023], https://www.bharatserums.com/assets/pdf/products/Upxiga(Liquid).pdf
  2. Qiancheng Xu et al; Ulinastatin is effective in reducing mortality for critically ill patients with sepsis: a causal mediation analysis; Scientific Reports; [Published on 25/09/2018]; [Accessed on 27/07/2023]; http://www.ncbi.nlm.nih.gov/pmc/articles/pmc6156583/
  3. Ling-Zhang wang et al; Effect of Ulinastatin on serum inflammatory factors in Asian patients with acute pancreatitis before and after treatment: a meta-analysis; International Journal of Clinical Pharmacology and Therapeutics; [Published on Nov 2016]; [Accessed on 27/07/2023]; https://pubmed.ncbi.nlm.nih.gov/27569736/

Safety Advice

Pregnancy: Consult your doctor If you are pregnant or planning to become pregnant and require treatment with Ulinafic 1,00,000IU Injection, it is crucial to consult your healthcare provider.

Lungs: Consult your doctor If you have a lung condition or are considering Ulinafic 1,00,000IU Injection treatment for any respiratory issue, it is vital to consult with a qualified healthcare professional. They can assess your medical history, perform a thorough evaluation, and determine the most appropriate treatment plan.

Breastfeeding: Consult your doctor If you are breastfeeding or planning to breastfeed and require treatment with Ulinafic 1,00,000IU Injection, it is crucial to discuss the matter thoroughly with your healthcare provider.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS