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Unitrexate 500mg Injection
Salt Composition: METHOTREXATE
- Manufacturer: UNITED BIOTECH PVT LTD
- Pack Size: 1 VIAL(s)
- Dosage Form: INJECTION
- Strength: 500MG
- Prescription Required
- Storage: Store the Unitrexate 500mg Injection below 25°C Do not freeze Protect the medicine from light and excessive moisture. Keep the medicine out of reach of children and pets If you forgot to take the injection, inform your healthcare professional immediately and reschedule the appointment.
₹525.00₹657.00
Inclusive of all taxes
Product Introduction
Unitrexate 500mg Injection contains Methotrexate as its active ingredient. It is an antimetabolite and immunosuppressant medicine used to treat several types of cancer, including acute lymphocytic leukemia (ALL), meningeal leukemia, non-Hodgkin’s lymphoma, osteosarcoma, cutaneous T-cell lymphoma, breast cancer, and head and neck cancer in adults. It is also prescribed for the treatment of severe psoriasis, a skin condition characterized by red, scaly patches, and rheumatoid arthritis in adults. Do not use Unitrexate 500mg Injection if you are allergic to Methotrexate or any of the other ingredients in this medicine. It should also be avoided in patients with kidney or liver disease, blood disorders, a weakened immune system, or in women who are pregnant or breastfeeding. Inform your doctor immediately if you experience symptoms such as coughing or spitting up blood, generalized muscle weakness, vision changes, or problems with thinking, memory, or orientation. This medicine may affect fertility. Avoid becoming pregnant during treatment and for six months after the final dose. Before starting therapy, tell your doctor if you have a stomach ulcer, an active infection, mild kidney disease, or have recently received any vaccinations. Unitrexate 500mg Injection may cause serious side effects even at low doses; therefore, regular medical follow-ups and routine laboratory tests are essential throughout treatment. Do not use this medicine if you are pregnant, breastfeeding, or planning to become pregnant.
Uses
To treat certain types of cancers To treat severe psoriasis To treat rheumatoid arthritis
How it works
Unitrexate 500mg Injection inhibits dihydrofolic acid reductase. Therefore, this medicine interferes with DNA synthesis, repair, and cellular replication. Actively proliferating tissues such as malignant cells, bone marrow, fetal cells, buccal and intestinal mucosa, and urinary bladder cells are, in general, more sensitive to this medicine. Blocking these slows down how fast cancer cells grow, spread, and suppress the immune system in autoimmune diseases.
How to Use
Always use this medicine as exactly prescribed by your doctor. Depending on the condition being treated, your physician decides the dose, dosage, and frequency of this injection. Unitrexate 500mg Injection is injected into a vein (intravenously) or into muscle (intramuscularly). Do not self-administer this medicine.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Common Hairloss Photosensitivity Rash Diarrhea, Nausea and Vomiting Decreased WBC and platelet count Dizziness Tiredness, fever, and shivering Blurred vision Serious Severe allergic reactions Spitting or coughing blood Chest pain Weakness on one side of the body Muscle weakness
Expert Tips
Avoid getting vaccines while using this medicine. This drug can cause sun sensitivity, so use sunscreen when going outdoors. Unitrexate 500mg Injection affects male and female infertility; consult your doctor before initiating the treatment if this concerns you. Male patients with female partners with reproductive potential should use an effective form of birth control during the treatment and 3 months after the last dose. Do not consume alcohol while receiving this medicine because this may increase the risk of liver damage. This medicine may make you bleed, bruise, or get infections more easily. Take precautions to prevent illness and injury. Wash your hands often. Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments. Inform your physician if you develop sores or white patches on your lips, mouth, or throat while using this medicine.
References
- Methotrexate tablet - Patient Information Leaflet (PIL) - (emc) [Internet]. www.medicines.org.uk. [Revised March 2022] [cited 2023 Jun 2]. Available from: https://www.medicines.org.uk/emc/product/511/smpc
- Hospira, Methotrexate Tablet, Food and drug administration. acess.fda.gov. [Revised August 2020] [cited 2023 Jun 2]. Available from: https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/040054s015,s016,s017.pdf
- Goodman & Gilmanâs, The Pharmacological Basis of Therapeutics, Pharmacotherapy of inflammatory bowel disease, 12th edition, 2011, 1358.
- KD Tripathi, Essentials of Medical Pharmacology, Antirheumatoid and antigout drugs, 7th edition, 2013, 211.
Safety Advice
Pregnancy: unsafe Do not use Unitrexate 500mg Injection during pregnancy because it can cause birth defects. Inform your physician if you are pregnant, suspecting pregnancy, or planning to get pregnant during the treatment. Use effective contraception during the treatment and for six months after the last dose.
Lungs: Consult your doctor Unitrexate 500mg Injection should be cautiously used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.
Breastfeeding: unsafe Breastfeeding is not recommended in patients taking Unitrexate 500mg Injection because the medicine passes into the breast milk in small amounts and may harm your baby. Do not breastfeed during the treatment.
Disclaimer
The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.