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Upxiga 100000IU Injection
Salt Composition: ULINASTATIN
- Manufacturer: LUPIN LTD
- Pack Size: 1 VIAL(s)
- Dosage Form: INJECTION
- Strength: 100000IU
- Prescription Required
- Storage: Store at temperature 2°C - 8°C Keep away from moisture, heat, and light. It should not be frozen. Keep away from children and pets.
₹2489.00₹3828.28
Inclusive of all taxes
Product Introduction
Upxiga 100000IU Injection contains Ulinastatin as its active ingredient. Also known as a urinary trypsin inhibitor (UTI), it is a medicine used in several countries for its anti-inflammatory and immunomodulatory properties. Originally isolated from human urine, Ulinastatin has been extensively studied for its potential therapeutic benefits in various inflammatory conditions. Its primary indication is the treatment of acute pancreatitis, a condition characterized by inflammation of the pancreas. It works by inhibiting specific enzymes and inflammatory mediators, thereby helping to reduce inflammation and lessen the severity of the disease. In addition, Upxiga 100000IU Injection has been investigated for use in conditions such as sepsis (a severe bacterial infection), multiple organ failure, and acute respiratory distress syndrome (ARDS). Its ability to regulate the immune response and suppress excessive inflammation may help reduce tissue damage in these serious conditions. Upxiga 100000IU Injection should not be used in patients with a known allergy or hypersensitivity to Ulinastatin or any of the ingredients in the formulation. Limited clinical data are available regarding its safety and effectiveness in certain groups, including children and elderly patients; therefore, it should be used with caution and under close medical supervision in these populations. This medicine may also interfere with certain laboratory tests, potentially affecting the accuracy of test results, so inform your healthcare provider if you are receiving Upxiga 100000IU Injection before undergoing diagnostic investigations. Do not discontinue this medicine abruptly, especially in critically ill patients, unless advised by your doctor, as sudden withdrawal may lead to adverse effects.
Uses
Upxiga 100000IU Injection is used to treat the following: Acute pancreatitis Sepsis Acute respiratory distress syndrome
How it works
Upxiga 100000IU Injection's mechanism of action involves inhibiting various proteolytic enzymes, such as trypsin and elastase, which are crucial in promoting inflammation and tissue damage. By suppressing these enzymes, this medication reduces the activation of inflammatory pathways and modulates the immune response, ultimately leading to decreased inflammation and potential mitigation of tissue injury.
How to Use
Upxiga 100000IU Injection is administered intravenously (vein injection) under medical supervision. Your healthcare professional will determine the specific dosage and administration guidelines based on your condition and needs.
Side Effects
Upxiga 100000IU Injection causes some side effects like all medications, although not everyone will experience them. Serious: Severe allergic reactions (difficulty breathing, swelling of the face or throat, hives, itching) Anaphylaxis (a life-threatening allergic reaction) Signs of an infection (fever, persistent sore throat) Changes in kidney function (changes in urine output, swelling of the legs or ankles) Abnormal bleeding or bruising Liver problems (yellowing of the skin or eyes, dark urine, abdominal pain) Neurological symptoms (confusion, seizures, difficulty speaking or moving) Common: Nausea Vomiting Diarrhea Skin rashes or itching Headache Dizziness Fever or chills Injection site reactions (pain, redness, or swelling)
Expert Tips
Patients with known hypersensitivity to Upxiga 100000IU Injection or any of its components should not use the medication. Regular monitoring of kidney and liver function is essential, and dose adjustments may be necessary for patients with impaired organ function. Caution is advised in pregnant and breastfeeding individuals, and the medication should only be used if needed and under medical supervision. Close monitoring for signs of allergic reactions, infections, and changes in blood counts is recommended. Patients with a history of gastrointestinal or bleeding disorders should be closely monitored during treatment. It's important to discuss all medical conditions and medications with the healthcare provider to ensure the safe and effective use of these medications.
References
- Bharat Serums and Vaccines Limited, [Accessed on 27th July 2023], https://www.bharatserums.com/assets/pdf/products/Upxiga(Liquid).pdf
- Qiancheng Xu et al; Ulinastatin is effective in reducing mortality for critically ill patients with sepsis: a causal mediation analysis; Scientific Reports; [Published on 25/09/2018]; [Accessed on 27/07/2023]; http://www.ncbi.nlm.nih.gov/pmc/articles/pmc6156583/
- Ling-Zhang wang et al; Effect of Ulinastatin on serum inflammatory factors in Asian patients with acute pancreatitis before and after treatment: a meta-analysis; International Journal of Clinical Pharmacology and Therapeutics; [Published on Nov 2016]; [Accessed on 27/07/2023]; https://pubmed.ncbi.nlm.nih.gov/27569736/
Safety Advice
Pregnancy: Consult your doctor If you are pregnant or planning to become pregnant and require treatment with Upxiga 100000IU Injection, it is crucial to consult your healthcare provider.
Lungs: Consult your doctor If you have a lung condition or are considering Upxiga 100000IU Injection treatment for any respiratory issue, it is vital to consult with a qualified healthcare professional. They can assess your medical history, perform a thorough evaluation, and determine the most appropriate treatment plan.
Breastfeeding: Consult your doctor If you are breastfeeding or planning to breastfeed and require treatment with Upxiga 100000IU Injection, it is crucial to discuss the matter thoroughly with your healthcare provider.
Disclaimer
The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.