Valest 1mg Tablet

Valest 1mg Tablet contains estradiol, an active ingredient belonging to vaginal Hormone Replacement Therapy (HRT) medicines. It is an estrogen that is chemically identical to the hormone naturally produced by women's ovaries. Valest 1mg Tablet is indicated for menopausal symptoms including vaginal atrophy (dryness or irritation of the vagina) in elderly women who have completed menopause.

Do not use Valest 1mg Tablet if you are allergic to estradiol or any of its constituents. It is contraindicated in patients with breast cancer or any oestrogen receptor-sensitive cancer. Do not use this medicine if you have a clotting disorder, blood clots in the veins (lungs or legs), or unexplained vaginal bleeding. Avoid Valest 1mg Tablet if you have had a heart attack, stroke, angina, or abnormal liver function tests. It is not given to patients with porphyria, a rare inherited blood disorder.

Estrogen intake elevates the risk of gallbladder disease. Discontinue use if you experience cholestatic jaundice, severe hypertriglyceridemia, severe hypercalcemia, or vision loss. Patients receiving thyroid replacement treatment require monitoring. Inform your doctor if you have vaginal bleeding, heart, kidney, lung or liver problems, diabetes, asthma, high blood pressure, or hearing disorder. Speak with your doctor if you are planning pregnancy, think you may be pregnant, or are breastfeeding. Discuss your complete medical history with your healthcare provider. Inform your healthcare provider about all medicines you are taking, including herbal, vitamin, and over-the-counter medicines.

Valest 1mg Tablet is used in the treatment of the following: Relieve menopausal symptoms of 'vaginal atrophy' (in the vagina such as dryness or irritation) Treatment for hypogonadism, castration, or primary ovarian failure-related hypoestrogenism Preventing osteoporosis after menopause

Valest 1mg Tablet primarily acts by binding to estrogen receptors (ERs) present on the surface of target cells upon binding to its receptor, Valest 1mg Tablet induces a conformational change in the receptor, leading to its activation. Valest 1mg Tablet replaces estrogen (female sex hormone) and prevents the symptoms of menopause, like vaginal irritation or dryness.

Take Valest 1mg Tablet exactly as prescribed by your healthcare provider. Do not adjust the dosage or frequency without consulting your doctor. Take your Valest 1mg Tablet at the same time each day to maintain a consistent level of hormones in your body. Swallow the Valest 1mg Tablet whole with a glass of water. Do not crush, chew, or break the tablet, as this may affect its effectiveness or increase the risk of side effects.

Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them. Common side effects of Valest 1mg Tablet are: Headache Stomach pain Vaginal bleeding Discharge or discomfort. Serious side effects of Valest 1mg Tablet are: Ovarian cancer Blood clots Heart attack Breast lumps Stroke

It is recommended to examine your breast (mammogram) to avoid the risk of breast cancer caused by the drug and inform your doctor if you have any changes in skin colour. Don't apply it on your breast, eye, or other part of the body apart from the application site. Inform your doctor if you have uterus cancer or a history of blood clots. Regularly monitoring liver function tests, thyroid tests, bone mineral density, and blood pressure is advised as treatment with Valest 1mg Tablet can alter these values.