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Vfend 50mg Tablet

Salt Composition: VORICONAZOLE

₹2778.00₹3354.38

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Vfend 50mg Tablet

Categories: Infectious Disease

Conditions: Antifungal

Product Introduction

Vfend 50mg tablet is an antifungal medication containing voriconazole as its active ingredient. It belongs to the class of fungal ergosterol synthesis inhibitors. It is prescribed for severe, life-threatening fungal infections and as prophylaxis in high-risk patients, including those who have received bone marrow transplantation. This medicine should not be administered to children younger than 2 years of age. Do not take Vfend tablet if you are allergic to voriconazole or any other ingredient in the formulation. Before taking Vfend 50mg tablet, inform your doctor if you have had an allergic reaction to other azoles, have a history of or current liver disease, or have cardiomyopathy, irregular heartbeat, slow heart rate, or long QTc syndrome on electrocardiogram (ECG). Additionally, avoid sunlight and sun exposure during treatment; protect skin with clothing and high-SPF sunscreen. Children should follow these precautions as well. Common side effects include fever, rash, nausea, vomiting, diarrhoea, headache, swelling of the extremities, abdominal pain, and breathing difficulties. While taking Vfend 50mg tablet, promptly inform your doctor if you experience sunburn, severe skin rash or blisters, bone pain, signs of adrenal insufficiency (chronic fatigue, muscle weakness, loss of appetite, weight loss, abdominal pain), or signs of Cushing's syndrome (weight gain, fatty hump, rounded face, darkened skin, thinning skin, easy bruising, high blood sugar, excessive hair growth, excessive sweating). Inform your doctor if you have a known intolerance to certain sugars before taking this medicine, as it contains lactose.

Uses

Invasive Aspergillosis Candidemia in non-neutropenic patients Esophageal candidiasis Fungal infections (caused by Scedosporium apiospermum, Fusarium spp., and Fusarium solani) Candida infections Fungal infections in high-risk bone marrow transplant patients

How it works

Vfend 50mg tablet works by blocking the production of ergosterol, disrupting fungal cell membranes and leading to cell death, ultimately eliminating the infection.

How to Use

Take the Vfend 50mg tablet as your physician advises. Usually, the tablets will be taken with or without food. Do not crush, chew, or open the medicine. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. Only stop taking the tablet if your doctor advises you to stop.

Side Effects

Vfend tablet side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious Rash Visual disturbances Liver problems Arrhythmias and QT prolongation Jaundice (Changes in blood tests of liver function) Pancreatitis (inflammation of the pancreas) Common Fever, headache Nausea, vomiting, diarrhea Swelling of the extremities Itchiness and rashes Sinusitis Pain in the stomach, back Blood in urine Seizures Low BP Hair loss Low levels of glucose, sodium, potassium, WBC, platelet Neutrophil counts in the blood.

Expert Tips

Liver and heart patients should take Vfend 50mg tablet cautiously and inform their doctor about all the underlying medical conditions. Do not stop the medicine until your doctor advises. Do not double-dose the medicine to make up for a forgotten dose. Unless your doctor advises, do not consume this medicine if you are pregnant or breastfeeding while taking Vfend 50mg tablet. Notify your doctor if you experience any serious side effects. Your medical professional will inform you if you need any dose adjustments. Contact your doctor for more information.

References

  1. Pfizer, Electronic Medicines Compendium (EMC), [Revised on Jul 2021] [Accessed on 02nd June 2023], https://www.medicines.org.uk/emc/files/pil.7976.pdf
  2. D.H. Dockrell, S. Sundar, B.J. Angus, R.P. Hobson, Infectious disease, Davidson’s Principles and Practice of Medicine, 22nd Edition, 2014, 293-386.
  3. Dr. Reddy’s Laboratories (UK) Ltd., Electronic Medicines Compendium (EMC), [Revised on July 2022] [Accessed on 02nd June 2023] PACKAGE LEAFLET: INFORMATION FOR THE USER (medicines.org.uk)

Safety Advice

Pregnancy: Consult your doctor 0mg tablet during pregnancy unless directed by your doctor. Use effective contraception and notify your doctor immediately if you become pregnant while taking medicine.

Lungs: unsafe It is unknown whether Vfend 50mg tablet is safe for patients with lung problems. Inform your physician if you have any lung disease before starting the treatment. Contact your doctor if you experience any lung-related symptoms.

Breastfeeding: Consult your doctor Limited information is available on using Vfend 50mg tablet during breastfeeding. So, before starting the treatment, inform your doctor if you are breastfeeding. Contact your doctor for more information.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS