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Voraze 200mg Injection

Salt Composition: VORICONAZOLE

₹1042.00₹2433.05

Inclusive of all taxes

Voraze 200mg Injection

Categories: Infectious Disease

Conditions: Antifungal

Product Introduction

Voraze 200mg injection is an antifungal medication containing voriconazole, a fungal ergosterol synthesis inhibitor. It is prescribed for severe, life-threatening fungal infections and as preventive therapy for high-risk patients, including those who have undergone bone marrow transplantation. This medicine must not be administered to children under 2 years of age. Do not use Voraze 200mg injection if you are allergic to voriconazole or any other constituent. Before commencing voriconazole, inform your doctor if you have experienced allergic reactions to other azole medications, have or have had liver disease, cardiomyopathy, irregular heartbeat, slow heart rate, or 'long QTc syndrome' (an electrocardiogram abnormality). During treatment, avoid sunlight and sun exposure; protect skin with clothing and high-SPF sunscreen. Children must observe these same precautions. Common side effects include fever, rash, nausea, vomiting, diarrhoea, headache, swelling of extremities, stomach pain, and breathing difficulties. While taking this medicine, promptly report to your doctor if you experience sunburn, severe skin rash or blisters, bone pain, signs of adrenal insufficiency (persistent fatigue, muscle weakness, loss of appetite, weight loss, abdominal pain), or signs of Cushing's syndrome (weight gain, fatty hump, rounded face, darkened skin, thin skin, easy bruising, elevated blood sugar, excessive hair growth, excessive sweating). Inform your doctor if you have a known intolerance to certain sugars before taking Voraze 200mg injection, as this medicine contains lactose.

Uses

Invasive Aspergillosis Candidemia in non-neutropenic patients Esophageal candidiasis Fungal infections (caused by Scedosporium apiospermum, Fusarium spp., and Fusarium solani) Candida infections Fungal infections in high-risk bone marrow transplant patients

How it works

Voraze 200mg injection works by blocking the production of ergosterol, disrupting fungal cell membranes and leading to cell death, ultimately eliminating the infection.

How to Use

Voraze 200mg injection will be administered to you by a healthcare professional in a hospital setting. It is usually administered in muscle or vein (intravenous). Your doctor will decide the dose, route of administration, and frequency based on your disease condition and other factors.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious Rash Visual disturbances Liver problems Arrhythmias and QT prolongation Jaundice (Changes in blood tests of liver function) Pancreatitis (inflammation of the pancreas) Common Fever, headache Nausea, vomiting, diarrhea Swelling of the extremities Itchiness and rashes Sinusitis Pain in the stomach, back Blood in urine Seizures Low BP Hair loss Low levels of glucose, sodium, potassium, WBC, platelet Neutrophil counts in the blood.

Expert Tips

Liver and heart patients should take Voraze 200mg injection cautiously and inform their doctor about all the underlying medical conditions. Do not stop the medicine until your doctor advises. Do not double-dose the medicine to make up for a forgotten dose. Unless your doctor advises, do not consume this medicine if you are pregnant or breastfeeding while taking Voraze 200mg injection. Notify your doctor if you experience any serious side effects. Your medical professional will inform you if you need any dose adjustments. Contact your doctor for more information.

References

  1. Pfizer, Electronic Medicines Compendium (EMC), [Revised on Jul 2021] [Accessed on 02nd June 2023], https://www.medicines.org.uk/emc/files/pil.7976.pdf
  2. D.H. Dockrell, S. Sundar, B.J. Angus, R.P. Hobson, Infectious disease, Davidson’s Principles and Practice of Medicine, 22nd Edition, 2014, 293-386.
  3. Istituto Biochimico Italiano G. Lorenzini S.p.A., Electronic Medicines Compendium (EMC), [Revised on March 2022] [Accessed on 02nd June 2023] pil.11014.pdf (medicines.org.uk)

Safety Advice

Pregnancy: Consult your doctor Avoid taking Voraze 200mg injection during pregnancy unless directed by your doctor. Use effective contraception and notify your doctor immediately if you become pregnant while taking medicine.

Lungs: Consult your doctor It is unknown whether Voraze 200mg injection is safe for patients with lung problems. Inform your physician if you have any lung disease before starting the treatment. Contact your doctor if you experience any lung-related symptoms.

Breastfeeding: Consult your doctor Limited information is available on using Voraze 200mg injection during breastfeeding. So, before starting the treatment, inform your doctor if you are breastfeeding. Contact your doctor for more information.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS