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Xolabin 750000IU Injection
Salt Composition: POLYMYXIN B
- Manufacturer: FUSION HEALTH CARE PVT LTD
- Pack Size: 1 VIAL(s)
- Dosage Form: INJECTION
- Strength: 750000IU
- Prescription Required
- Storage: Store at room temperature, between 20°C to 25°C (68°F to 77°F). Keep away from moisture, heat, and light. It should not be frozen. Keep away from children and pets.
₹2280.00₹4958.44
Inclusive of all taxes
Product Introduction
Xolabin 750000IU contains the active ingredient Polymyxin B, an antibiotic used to treat a variety of serious bacterial infections, particularly those caused by Gram-negative bacteria. It is generally prescribed when other antibiotics are ineffective or when infections are caused by multi-drug-resistant bacteria. This medicine may be used to treat conditions such as urinary tract infections (UTIs), pneumonia, bacterial skin infections, and ventilator-associated pneumonia (VAP). A urinary tract infection is a bacterial infection affecting the bladder, urethra, or kidneys. Pneumonia is an infection that causes inflammation of the lungs and may result from bacteria, viruses, or fungi. Ventilator-associated pneumonia is a serious lung infection that develops in patients receiving mechanical ventilation, usually due to bacteria entering the lungs through the breathing tube.
Xolabin 750000IU is a potent antibiotic used to combat severe bacterial infections, particularly those caused by resistant organisms when standard antibiotic therapies are no longer effective. Although it plays a vital role in managing life-threatening infections, it requires careful medical supervision because it may affect the kidneys and nervous system. Due to its effectiveness against difficult-to-treat bacteria, it remains an important treatment option in critical care settings.
Do not use Xolabin 750000IU if you have a known allergy or hypersensitivity to Polymyxin B or other related antibiotics. This medicine has the potential to cause kidney damage (nephrotoxicity), so patients with kidney disease or impaired kidney function should inform their doctor before starting treatment. Your healthcare provider may perform regular kidney function tests during therapy to minimise the risk of complications. In children, dosage adjustments may be required to reduce the risk of kidney toxicity and nervous system-related side effects. Older adults should also be closely monitored, as age-related decline in kidney function may increase the likelihood of adverse effects during treatment.
Uses
Xolabin 750000IU injection is used in the following: Bacterial infections Alternative for multi-drug resistant bacteria Urinary tract infections (UTIs) Pneumonia Bacterial skin infections Ventilator-associated pneumonia (VAP) Skin infections
How it works
Xolabin 750000IU injection acts by disrupting the outer membrane of Gram-negative bacteria. It binds to and interacts with the lipopolysaccharide layer, a crucial component of the bacterial cell wall, causing membrane destabilization. This leads to increased permeability, leakage of cell contents, and eventual cell death. By targeting the outer membrane, This medication effectively neutralizes Gram-negative bacteria, making it particularly valuable in treating infections caused by these bacteria, especially in cases of multidrug resistance where other antibiotics may not be effective.
How to Use
Xolabin 750000IU Injection should be taken exactly as prescribed by a healthcare professional. It is available in various forms, such as tablets or capsules. The dosage and frequency depend on the medical condition being treated. This medication can be taken with or without food, and patients should not adjust the dosage or stop taking it without medical guidance. Following the doctor's instructions is very important, and if you experience any possible side effects, make sure to inform your healthcare provider right away.
Side Effects
Xolabin 750000IU Injection causes some side effects like all medications, although not everyone will experience them. Serious: Allergic reactions Kidney damage Neurotoxicity Common: Injection site reactions (for intravenous administration) Nausea or vomiting Diarrhea Loss of appetite Rash or skin irritation (for topical application)
Expert Tips
When using Xolabin 750000IU Injection, it is important to take certain precautions for safe and effective treatment. Inform your healthcare provider about any known allergies, especially to antibiotics like colistin. For individuals with impaired kidney or liver function, dose adjustments and close monitoring may be necessary. Be vigilant for potential adverse effects, such as neurotoxicity, skin irritation, or allergic reactions, and report any new or worsening symptoms promptly. Avoid alcohol consumption while on using this medication to prevent interactions and worsened side effects. Complete the full prescribed course of treatment, even if you start feeling better, to avoid bacterial resistance and superinfections. Follow your healthcare provider's advice on dosage and monitoring. Keep all healthcare providers informed about your medication use to prevent potential drug interactions. Store this medicine correctly and dispose of any unused medication as recommended. Adhering to these precautions will help ensure the safe and successful use of this medication.
References
- Goodman & Gilmanâs, The Pharmacological Basis of Therapeutics, Protein synthesis inhibitors and miscellaneous antibacterial agents, 12th edition, 2011, 1538 -1539.
- KD Tripathi, Essentials of Medical Pharmacology, Macrolide and other antibacterial antibiotics, 7th edition, 2013, 759.
- Bedford Laboratories, US Food and Drug Administration, [Revised on June 2011] [ Accessed on 01th August 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/060716Orig1s020Lbl.pdf
Safety Advice
Pregnancy: Consult your doctor During pregnancy, it is crucial to consult a healthcare professional before using Xolabin 750000IU Injection. The potential benefits and risks to both the mother and the baby should be carefully evaluated, and alternative treatments should be considered if possible.
Lungs: Consult your doctor When using Xolabin 750000IU Injection to treat lung infections, adhere to the prescribed treatment plan provided by your healthcare professional. Monitor for any potential side effects and avoid exposure to lung irritants, such as smoke and pollutants, to support respiratory well-being during the treatment.
Breastfeeding: Consult your doctor Consult a healthcare professional before using Xolabin 750000IU Injection. Limited systemic absorption minimizes the risk of it passing into breast milk.
Disclaimer
The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.