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Xpreza 200mg Tablet

Salt Composition: AZACITIDINE

₹12000.00₹15000.00

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Xpreza 200mg Tablet

Categories: Oncology

Conditions: Anti Cancer

Product Introduction

Xpreza 200 mg tablet contains the active ingredient Azacitidine. It is indicated for the treatment of adults with certain blood disorders, including Myelodysplastic Syndrome (MDS), chronic myelomonocytic leukaemia, and Acute Myeloid Leukaemia (AML), in patients who are ineligible for stem cell transplantation. In Myelodysplastic Syndrome, the bone marrow fails to produce healthy blood cells due to impaired function. Acute Myeloid Leukaemia is a bone marrow malignancy characterised by the presence of incompletely formed blood cells in the bloodstream. Chronic myelomonocytic leukaemia is a rare blood malignancy resulting from an elevated count of monocytes within the white blood cell population.

Uses

Acute Myeloid Leukemia with 20-30% blasts in patients who are not eligible for Haemopoietic stem cell transplant High-risk Myelodysplastic syndrome (MDS)

How it works

Xpreza 200 mg tablet binds to RNA and DNA, interrupts their activity in actively multiplying cells, and exhibits a toxic effect on cancer cells.

How to Use

Take Xpreza 200 mg only under the supervision of your physician. Your physician will decide the dose based on your height, weight and general condition. The tablet is orally administered. Take it as a whole with water. Do not break, chew or crush the tablet.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious: Drowsiness Shivering Jaundice Stomach bloating Unusual bleeding or bruising Reduced urination Increased thirst Dizziness Confusion Chest pain Breathlessness Allergies Common: Disturbances in the blood count (RBC, WBC, Platelets) Nausea, vomiting, diarrhea Constipation Tiredness Skin reactions like redness and pain at the site of the tablet Decreased appetite Dizziness Pain in extremities Joint pain Stomach pain Headache Sore nose and throat Rashes and bruising

Expert Tips

Inform the doctor if the patient has any allergy reactions, respiratory problems, kidney, liver, or heart problems, and medication taken for different medical conditions before taking this tablet as they worsen the condition. Avoid using this tablet if the patient is planning for pregnancy or during pregnancy and in breastfeeding mothers as this medicine causes harmful effects on the developing baby. Take this tablet only under the supervision of the physician. Doctors will decide the dose based on the patient's height, weight, and general condition.

References

  1. K. Gaston and P.-S. Jayaraman, Transcriptional repression in eukaryotes: Repressors and repression mechanisms, Cellular and Molecular Life Sciences, [May 2003], 60(4):721-741, [Accessed on 5th Apr 2021] https://www.researchgate.net/publication/7094896_Transcriptional_repression_in_eukaryotes_Repressors_and_repression_mechanisms
  2. Roman M. Shapiro & Alejandro Lazo-Langner, Systematic review of azacitidine regimens in myelodysplastic syndrome and acute myeloid leukemia, BMC Hematology, 2018 [Accessed on 3rd Apr 2021] https://bmchematol.biomedcentral.com/articles/10.1186/s12878-017-0094-8
  3. Dr.Reddy’s Laboratories, [Revised on 8th Nov 2018] [Accessed on 5th Apr 2021] https://www.drreddys.com/media/743001/ac-pm-english.pdf

Safety Advice

Pregnancy: unsafe Xpreza 200 mg tablets are not intended for use during pregnancy. Talk to your physician if you are pregnant or think you could be pregnant.

Lungs: Consult your doctor Inform your physician before taking Xpreza 200 mg tablets if you have any lung problems.

Breastfeeding: unsafe Consult your physician for advice on taking Xpreza 200 mg tablets if you are a breastfeeding mother

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS