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Xtide 160mg Tablet

Salt Composition: ENZALUTAMIDE

₹7032.00₹9843.75

Inclusive of all taxes

Categories: Oncology

Conditions: Anti Cancer

Product Introduction

Xtide 160mg Tablet contains the active compound enzalutamide, which belongs to the class of medications called androgen receptor inhibitors. It is used to treat prostate cancer in men. It is suitable for treatment in men with high testosterone levels where previous treatments (hormonal therapy or testosterone-lowering surgery) that reduce testosterone no longer provide complete disease control. It is also suitable for treatment in metastatic cases where the cancer has spread from the prostate to other parts of the body and responds to hormone therapy or surgery to reduce testosterone levels. It is also used in cases of prostate cancer that is responsive to castration (surgical removal of testicles) but is not metastatic, with a high risk of metastasis and biochemical recurrence. It is not recommended to take Xtide 160mg Tablet if you are allergic to the active compound or any other ingredients of this medicine. It is not recommended for use in children and adolescents below the age of 18. Men are advised to use effective contraceptive methods during therapy and for 3 months after treatment since it has the ability to harm the developing foetus. Inform your doctor if you are pregnant or planning to become pregnant to discuss effective contraceptive methods. It is recommended to test your bone density during treatment. Before starting treatment, inform your physician if you have any infections, kidney, heart, or liver problems. Patients who have ischemic heart disease require close monitoring for risk factors. Inform your doctor immediately if you experience a seizure, worsening headache, disorientation, blindness, or any other vision problems. It is necessary to inform your physician about all medicines, over-the-counter drugs, vitamins, and herbal supplements you are taking before starting therapy.

Uses

Prostate cancer resistant to other treatments Metastatic prostate cancer reacts to hormone therapy or surgery to reduce testosterone levels Non-metastatic prostate cancer with a high chance of spread and recurrence

How it works

Xtide 160mg Tablet medicine acts by blocking the activity of androgens hormone (such as testosterone) by binding with androgen receptors. Xtide 160mg Tablet prevents the Androgen receptor from moving to its new site, which further lowers AR-mediated transcriptional activity and stops the growth of tumor cells. Xtide 160mg Tablet inhibits the AR complex's ability to bind to DNA, which stops the transcriptional activation of AR target genes. As a result, it reduces testosterone levels and halts the growth and division of prostate cancer cells.

How to Use

Xtide 160mg Tablet is usually taken orally, with or without food. The capsules should be swallowed whole with a glass of water and not crushed, chewed or broken. The dosage and frequency of Xtide 160mg Tablet will depend on various factors, including the patient's age, weight, overall health, and the type and stage of cancer being treated. It's important to follow the dosing instructions provided by a healthcare provider and not adjust the dosage or frequency without consulting with them first. Pregnant or potentially pregnant women shouldn't handle broken or damaged Xtandi tablets without wearing gloves or other protective gear. If a dose is missed, it should be taken as soon as possible unless it's within 6 hours of the next scheduled dose. In that case, the missed dose should be skipped, and the regular dosing schedule should be resumed. It's important not to take a double dose of abemaciclib to make up for a missed dose.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Common Tiredness Fall Hot flushes High blood pressure Headache Feeling anxious Dry skin Itching Difficult in remembering Restlessness Serious: Posterior Reversible Encephalopathy Syndrome (PRES) Blockage of the arteries (ischemic heart disease) Enlargement of breast in men (gynecomastia) Broken bones

Expert Tips

If you have been prescribed Xtide 160mg Tablet, it is important to follow the instructions provided by your healthcare provider and to report any side effects or concerns promptly. It is advised not to consume grape juice during the treatment. Stay hydrated by consuming lots of liquids, particularly if you get diarrhoea when using Xtide 160mg Tablet. It's critical to maintain a sufficient fluid intake because dehydration can exacerbate symptoms such as diarrhea and other gastrointestinal disorders. Even if you feel better or see a change in your symptoms, you should still talk to your doctor before stopping Xtide 160mg Tablet. It is recommended to monitor your blood counts and bone density at regular intervals. It is not advised for women, particularly for those who are nursing or pregnant. Notify your physician if you experience frequent urges to urinate, blood in your urine, or digestive issues. Inquire with your physician if you get discomfort in the bladder or colon, as the medication may result in bladder or colon cancer as a side effect. Remember to attend all scheduled appointments and follow-up visits with your healthcare provider to ensure your treatment is effective and any side effects are managed appropriately. With proper monitoring and management, Xtide 160mg Tablet can be an effective treatment option for prostate cancer.

References

  1. Astellas Pharma Europe B.V, Electronics Medicines Compendium(emc), [ Revised on December 2022] [ Accessed on 30/03/2024], https://www.medicines.org.uk/emc/files/pil.10318.pdf
  2. Astellas Pharma US Inc, United States Food and Drug Administration (US FDA), [ Revised on January 2022] [ Accessed on 30/03/2024], https://www.accessdata.fda.gov/drugsatfda_docs/label/2022/203415s018,213674s005lbl.pdf
  3. Astellas Pharma US, Inc, [Revised on November 2023], [Accessed on 30/03/2024], https://www.astellas.us/docs/12A005-ENZ-WPI.PDF
  4. KD Tripathi, Essentials of Medical Pharmacology, Adrenergic system and drugs, 7th edition, 2013, 134.

Safety Advice

Pregnancy: unsafe Xtide 160mg Tablet is not indicated for use in women. It is unsafe for pregnant women as it may cause foetal harm. It can cause damage to a developing baby if taken during pregnancy. It is important to use effective contraception.

Lungs: Consult your doctor It is unknown whether Xtide 160mg Tablet is safe for patients with lung problems. Inform your physician if you have any lung disease before starting the treatment. Contact your doctor if you experience any lung-related symptoms.

Breastfeeding: unsafe Xtide 160mg Tablet is not recommended during breastfeeding, as it is unknown if it is excreted in human milk. Because of the potential risk to the infant, breastfeeding is not recommended.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS