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Zexipag 400mcg Tablet
Salt Composition: SELEXIPAG
- Manufacturer: CIPLA LTD
- Pack Size: 10 TABLET(s) IN A STRIP
- Dosage Form: TABLET
- Strength: 400MCG
- Prescription Required
- Storage: Store Zexipag 400mcg Tablet below (25°C). Protect from light and moisture.
₹1193.00₹1490.63
Inclusive of all taxes
Product Introduction
Zexipag 400mcg Tablet is a pulmonary vasodilator containing the active ingredient Selexipag, a prostacyclin receptor agonist. It is used to treat pulmonary arterial hypertension (PAH) to improve exercise capacity and delay disease progression. Pulmonary arterial hypertension is a serious and rare medical condition characterised by elevated blood pressure in the arteries supplying the lungs. It affects the small blood vessels (arteries) in the lungs, causing their narrowing and increased resistance to blood flow.
Do not take this medication if you have known hypersensitivity or allergy to Selexipag or any component of this tablet. It is contraindicated in patients with severe coronary heart disease, unstable angina, recent myocardial infarction, decompensated cardiac failure, severe cardiac arrhythmia, or certain cardiac valve defects. It is also contraindicated if you have experienced a stroke within the preceding three months or any other cerebrovascular event that reduces blood supply to the brain. Concurrent use with gemfibrozil (a medication used to lower lipid levels) is contraindicated.
Inform your physician if you have thyroid dysfunction. Thyroid disorders may impact your treatment plan, and your doctor will assess the potential effects of this medication on your condition.
This medication is contraindicated during pregnancy as it may cause fetal harm. Breastfeeding is not recommended in patients taking Zexipag 400mcg Tablet because it is unknown whether this medicine is excreted into breast milk and whether it may harm the nursing infant.
Selexipag is metabolised and excreted by the kidneys. Patients with severe renal impairment or those undergoing dialysis require dosage adjustment or an alternative medication, as determined by your physician.
Uses
Treatment of pulmonary arterial hypertension (PAH)
How it works
Zexipag 400mcg Tablet works by activating the prostacyclin receptors in the blood vessels of the lungs. This activation leads to the relaxation and widening of the blood vessels, reducing the elevated blood pressure in the pulmonary arteries. By dilating the blood vessels, this drug improves blood flow and reduces the workload on the heart.
How to Use
Take the Zexipag 400mcg Tablet as advised by your physician. Do not crush, chew, or open the medicine. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. Only stop taking the tablet if your doctor advises you to stop.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious Headache Diarrhea Reddening of face Vomiting, nausea Pain in the jaws, muscles, legs, or joints Stuffy nose Common Weight loss Stomach pain Rashes Hyperthyroidism Reduced appetite
Expert Tips
Since this medication aims to reduce joint pain, swelling, and stiffness, it may take several weeks or months to experience the full benefits of Zexipag 400mcg Tablet, so be patient and continue taking it as directed.
References
- Janssen-Cilag Limited, Electronic medicines compendium (EMC), [Revised on June 2022] [ Accessed on 18th July 2023], https://www.medicines.org.uk/emc/files/pil.2163.pdf
- Actelion Pharmaceutical US, US Food and Drug Administration, [Revised on Dec 2017] [ Accessed on 18th July 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/207947s005lbl.pdf
- Olivier Sitbon et al.; Selexipag for the Treatment of Pulmonary Arterial Hypertension; The New England Journal of Medicine; Published on Dec 2015; Accessed on 18/07/2023; https://pubmed.ncbi.nlm.nih.gov/26699168/
Safety Advice
Pregnancy: unsafe Zexipag 400mcg Tablet is not recommended during pregnancy or if there is a possibility of becoming pregnant. It is advised for women to use appropriate contraceptive measures to prevent pregnancy while using this medication.
Lungs: safe Zexipag 400mcg Tablet is safe for patients with lung problems. Consult your doctor for more advice.
Breastfeeding: unsafe Breastfeeding is not recommended in patients taking Zexipag 400mcg Tablet because it is unknown whether the medicine passes into the breast milk and harms your baby.
Disclaimer
The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.