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Zyfol Injection 20ml

Salt Composition: PROPOFOL

₹76.00₹151.94

Inclusive of all taxes

Categories: Others

Conditions: Anaesthetics

Product Introduction

Zyfol 20ml injection contains propofol, a general anaesthetic. General anaesthetics induce unconsciousness to permit surgical operations or other procedures. They may also be used for sedation, keeping you drowsy but not fully asleep.

Zyfol 20ml injection is indicated to produce partial or complete reversible loss of consciousness in adults and children aged 1 month and above, to enable surgical procedures. It is also used to induce sleep in patients aged 16 years or older who are receiving mechanical ventilation in an Intensive Care Unit (ICU).

Do not use this medication if you are allergic to propofol or any of its ingredients. Inform your doctor if you have allergies to peanuts or soya, as this medication contains soya oil.

Before using this medication, inform your doctor, anaesthetist, or nurse if you have a history of seizures, elevated blood lipid levels, dehydration, or any other medical conditions affecting your heart, lungs, kidneys, or liver. Also disclose if you have experienced prolonged illness or have been diagnosed with mitochondrial disease. Communicating this information ensures your treatment plan is individualised according to your medical history and safety requirements.

Uses

Reversible loss of consciousness (General anesthesia)

How it works

The action of zyfol 20ml like all general anesthetics, needs to be better understood. However, it is thought to produce loss of consciousness by potentiating the actions of certain brain chemicals (neurotransmitter GABA) through the specific receptors (ligand-gated GABA A receptors) and decreasing the flow of chloride ions across the nerve cells required to maintain alertness.

How to Use

This medicine is given only in a hospital set up by a trained healthcare provider. It will be given to you as an injection into a vein, usually in the back of your hand or forearm. Your doctor will decide your most apt dosage based on age, body weight, and physical circumstances.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them. Serious Allergic reactions - symptoms of difficulty in breathing, swelling of the eyelids, face, or lips, rash or itching (especially affecting your whole body) Stress cardiomyopathy - symptoms of chest pain, shortness of breath, nausea, or an irregular heartbeat, especially if you are stressed. Common Injection site pain Low blood pressure Changes in your breathing pattern Slow heartbeat Nausea and Vomiting Headache Withdrawal symptoms - unusual behavior, sweating, shaking, and feeling anxious (in children) Flushing of the skin (in children)

Expert Tips

Please inform your doctor if you are on a sodium-controlled diet or have allergies to peanuts or soya, as zyfol 20ml contains these components. If the injection is administered over extended periods in intensive care, your doctor may prescribe a zinc supplement to prevent a decrease in your zinc levels. Before starting the treatment, it is essential to inform your doctor if you are allergic to any of these components or have any concerns. It is essential to trust your medical team and communicate openly with them. Zyfol 20ml injection is a powerful anesthetic used to induce and maintain anesthesia, and while it is generally safe, it is crucial to disclose your complete medical history, allergies, and any medications you are taking to your healthcare provider. Follow their instructions diligently, and be sure to inform them about any unusual sensations or discomfort during the procedure. It is natural to feel apprehensive, but focusing on the expertise of your medical team and openly communicating your concerns with your doctor can help ensure a safer and more comfortable experience.

References

  1. Mercury Pharmaceuticals Ltd, Electronic medicines compendium (EMC), [Revised on April 2022], [Accessed on 27th Sept 2023], https://www.medicines.org.uk/emc/files/pil.5492.pdf
  2. Fresenius Kabi USA, US Food and Drug Administration (FDA), [Revised on Aug 2022], [Accessed on 27th Sept 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2022/019627s069lbl.pdf
  3. KD Tripathi, Essentials of Medical Pharmacology, Drugs acting on central nervous system, 2019, 409-410
  4. Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, General Anesthetics and Therapeutic Gases, 2018, 390-391

Safety Advice

Pregnancy: unsafe Zyfol 20ml injection can pass the placental barrier and cause miscarriage, birth defects, or neonatal depression during pregnancy. Hence, If you are pregnant, think you may get pregnant, or planning to have a baby, inform your doctor for advice before taking this medicine. Zyfol 20ml injection is given to you only when it is considered essential by your doctor.

Lungs: Consult your doctor Zyfol 20ml injection is used with caution for severe breathing disorders. Before taking this medication, inform your doctor if you have any active lung disease.

Breastfeeding: unsafe Zyfol 20ml injection can be excreted into human breast milk and lead to neonatal depression if used during breastfeeding. Therefore, consult your doctor to determine when it's safe to resume breastfeeding while undergoing this medication.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS