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Zyrubin 10mg Injection

Salt Composition: EPIRUBICIN

₹363.00₹541.00

Inclusive of all taxes

Categories: Oncology

Conditions: Anti Cancer

Product Introduction

Zyrubin 10mg Injection contains Epirubicin Hydrochloride, an antineoplastic drug from the anthracycline class. It is indicated as adjuvant therapy in combination with other medications for breast cancer in patients following surgical tumour removal. The medicine is also used to treat cancers of the breast, ovaries, stomach, bowel, and lung. Additionally, it is employed in treating blood-forming tissue malignancies, including malignant lymphomas, leukaemias, and multiple myeloma.

Do not use this injection if you are allergic to Epirubicin or any other ingredient, are pregnant or breastfeeding, or have severe liver and bladder dysfunction. Inform your physician before treatment if you have kidney or liver problems, recent vaccination, or any acute toxicities including acute inflammation of the mouth, low white blood cell count, low platelet count, or active infections. This medicine may increase your risk of blood clots and may cause infertility in men and women; inform your physician if you are planning pregnancy. If sexually active, use effective contraception to prevent pregnancy.

Your physician will conduct regular laboratory tests to monitor the effects of this medicine. Common side effects of Zyrubin 10mg Injection include decreased white blood cells, decreased platelets, irregular menstruation, weakness, nausea or vomiting, diarrhoea, eye infection, skin rashes, or itchiness.

Uses

Zyrubin 10mg Injection is used in the treatment of the following: Breast cancer Stomach and bowel cancer Ovarian cancer Lung cancer

How it works

Zyrubin 10mg Injection inhibits DNA, RNA, and protein synthesis by exerting cytotoxic activity. It works by slowing or stopping the growth of the cancer cells. This medicine helps to selectively kill the cancer cells rather than the normal, healthy cells.

How to Use

It should only be administered by a trained doctor or nurse experienced in giving chemotherapy. The medicine will be given as an infusion into a vein. Do not self-administer the injection. Your doctor will decide the dose and duration of the treatment based on your disease severity and other factors.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Common: Hair loss Flushing Rash, itching Diarrhea Nausea and vomiting Anemia Decreased WBC and platelets Eye infection Irregular menstruation Serious: Congestive heart failure Increased blood urea levels Severe hypersensitivity reaction Lung problems

Expert Tips

Inform your physician if you are receiving radiation therapy with this medicine. This medicine may cause birth defects if either partner uses it during conception or pregnancy. Male patients with female partners of reproductive potential should use effective birth control during the treatment and for 3 months after the last dose. Do not breastfeed during the treatment and for 7 days after the last dose. The medicine may turn your urine red for 1 or 2 days after your treatment.

References

  1. Epirubicin hydrochloride 2 mg/ml solution for injection - Summary of Product Characteristics (SmPC) - (emc). Medicines.org.uk. [revised on 2016] [cited 2023 Mar 31]. Available from: https://www.medicines.org.uk/emc/product/6361/smpc
  2. HIGHLIGHTS OF PRESCRIBING INFORMATION - Epirubicin. [revised on 2019] [cited 2023 Mar 31]. Available from: https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/050778s024s025lbl.pdf
  3. KD Tripathi, Essentials of Medical Pharmacology, Anticancer drugs, 7th edition, 2013, 867

Safety Advice

Pregnancy: unsafe Zyrubin 10mg Injection is unsafe to administer in pregnant women because it may be a fetus. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant. Using an effective birth control method during the treatment and for 6.5 months after your last dose is necessary.

Lungs: Consult your doctor It is unknown whether Zyrubin 10mg Injection can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.

Breastfeeding: unsafe Breastfeeding is not recommended in patients taking Zyrubin 10mg Injection because the medicine passes into the breast milk in small amounts and may harm your baby.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS