CLINDAMYCIN

Clindamycin was approved by the U.S. Food and Drug Administration (FDA) on November 27, 2000, for treating bacterial infections. It is a lincosamide medicine that belongs to the antibiotic class of medications.

Clindamycin is used to treat certain serious bacterial infections by inhibiting bacterial growth.

Clindamycin will be administered to you by a healthcare professional in a hospital setting. It is usually administered in muscle or vein (intravenous). Your doctor will decide the dose, route of administration, and frequency based on your disease condition and other factors.

The most common side effects of Clindamycin are inflammation of the veins (blood clot), abnormal liver function, and rash. Serious side effects while taking Clindamycin are sepsis (blood poisoning) and angioedema (swelling in the deeper layers of the skin).

Clindamycin should not be consumed if you are allergic to Clindamycin, Lincomycin, or any of its ingredients in the medication. Inform your doctor if you have a history of antibiotic-related diarrhea or stomach or intestinal issues. Notify your doctor immediately if you have severe or prolonged diarrhea, including bloody diarrhea. Mention any allergies (such as hay fever, asthma, or eczema), kidney, or liver problems to your doctor.

Notify your doctor if you are pregnant, planning to get pregnant, or think you may be pregnant or breastfeeding. Seek medical attention if you experience decreased urine output, fluid retention, swelling reactions, shortness of breath, or nausea. Notify your doctor immediately if you experience severe, prolonged, or bloody diarrhea during or after using Clindamycin Injection, as it may be a sign of bowel inflammation (pseudomembranous colitis) that can occur weeks after antibiotic treatment.

Patients with liver or kidney disease should use Clindamycin with caution and disclose all underlying medical conditions to their doctor. Do not discontinue the medicine without medical advice. Do not take a double dose to compensate for a missed dose. Avoid breastfeeding while taking Clindamycin. Inform your doctor if you experience any serious side effects. Your doctor will determine whether dose adjustments are necessary. Seek medical advice for further information. If you are undergoing a surgical procedure or hospitalisation, inform your doctor of your Clindamycin use, as it may interact with certain medications and potentiate their effects. Do not freeze the medicine. Store below 25°C. Always verify the expiry date before use.

Focus Pharmaceuticals Limited, Electronic Medicines Compendium (EMC), [Revised on March 2022] [Accessed on 8th June 2023], *Microsoft Word - CLINDA~1 (medicines.org.uk) Pfizer, US Food and Drug Administration, [ Revised on October 2007] [ Accessed on 8th June 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2008/050441s055,050639s016lbl.pdf Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Protein Synthesis Inhibitors and Miscellaneous Antibacterial Agents,12th edition, 2011,1534. .KD Tripathi, Essentials of Medical Pharmacology, Macrolide, Lincosamide, Glycopeptide, and Other Antibacterial Antibiotics, 7th edition, 2013, 756.