MUPIROCIN
Background and Date of Approval
Mupirocin is a topical antibiotic agent that acts on bacterial cell membranes. It received U.S. FDA approval on 12 April 2002 for the treatment of impetigo.
Uses
Mupirocin is prescribed for the topical treatment of impetigo. Impetigo is a common and highly contagious bacterial skin infection that mainly affects children.
How is it administered?
It can be used for external purposes only. To use this ointment, wash the affected area, apply a thin layer using gentle circular motions, and repeat two to three times a day or as directed. Avoid applying to open wounds or broken skin, and follow specific instructions from your healthcare provider.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Mupirocin ointment generally does not cause any side effects. However, if you experience unfamiliar symptoms after using this ointment, consult your physician.
Warnings
This drug is contraindicated and should not be used if you have a known hypersensitivity or allergy to Mupirocin or any of its components. If you have experienced an allergic reaction to this drug in the past, you should avoid using it. This ointment is intended for external use only and should not come into contact with the eyes, nose, mouth, or other mucous membranes. If accidental contact occurs, it should be rinsed thoroughly with water
Precautions
This medicine is not recommended for use on deep or puncture wounds. It is best to consult a healthcare professional for appropriate wound care and treatment in these cases. If you are a pregnant or breastfeeding woman, please consult your doctor before using this drug.
Word of Advice
Do not share your Mupirocin ointment with others, even if they present with similar symptoms. It is prescribed specifically for your condition, and use without medical advice may not be effective for others. Avoid contact with the eyes, nose, mouth, or other mucous membranes. If accidental contact occurs, rinse the area thoroughly with water. Complete the full duration of treatment as prescribed, even if symptoms improve or resolve before finishing the course. This ointment helps ensure complete eradication of the infection. Use a clean cotton swab or sterile applicator to apply a thin layer to the affected area. Avoid using your fingers to minimise the risk of contamination.
References
Mupirocin ointment, 2% rx only - Food and Drug Administration. Available at: https://www.accessdata.fda.gov/drugsatfda_docs/label/2002/50788_Mupirocin_lbl.pdf (Accessed on 11 May 2023). Goodman & Gilmanâs, The Pharmacological Basis of Therapeutics, Chemotherapy of microbial diseases, 12th edition, 2011, 1544. Bertram.G.Katzung, Basic and Clinical Pharmacology, Cancer Chemotherapeutic drugs, 14th edition, 2017, 896, and 1070. KD Tripathi, Essentials of Medical Pharmacology,Macrolide and other Antibacterial Antibiotics, 7th edition, 2013, 759.
Frequently Asked Questions
What is Mupirocin used for?
Mupirocin is an antibiotic used topically to treat bacterial skin infections, including impetigo (a common skin infection), folliculitis (hair follicle infection), and certain types of wound infections.
How does Mupirocin work?
Mupirocin works by inhibiting the growth and spread of bacteria. It specifically targets the bacteria's ability to produce proteins necessary for survival, ultimately leading to their elimination.
How should I apply Mupirocin ?
Clean the affected area thoroughly with mild soap and water, then pat it dry. Apply a thin layer of the Mupirocin to the affected area, usually two to three times a day or as directed by your doctor. Avoid using excessive amounts of ointment.
Can Mupirocin be used on open wounds?
Yes, Mupirocin can be used on open wounds as long as your healthcare professional mentions no contraindications. It helps prevent or treat bacterial infections in wounds and promotes healing.
Whether Mupirocin ointment can be used for pus infections?
Yes, Mupirocin can be used to treat skin infections that involve pus. Consult your doctor for a clear diagnosis and treatment recommendations.
How long should I use Mupirocin ointment?
The main duration of treatment depends on the specific infection and your healthcare professional's instructions. It is necessary to complete the full treatment regimen as prescribed, even if the symptoms improve before completion.