SAROGLITAZAR
Background and Date of Approval
The U.S. FDA approved Saroglitazar for neurological disorders on February 13. Saroglitazar is a dual peroxisome proliferator-activated receptor (PPAR) agonist. It functions by managing elevated cholesterol and triglycerides, as well as blood glucose levels in patients with type 2 diabetes.
Uses
Saroglitazar is used to treat diabetic dyslipidemia (an abnormal amount of lipids in the blood) and hypertriglyceridemia (high level of triglycerides in the blood) in patients with type 2 diabetes mellitus that is not controlled by statin therapy.
How is it administered?
Take the Saroglitazar as your physician advises. Do not crush, chew, or open the medicine. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. Only stop taking the tablet if your doctor advises you to stop.
Side Effects
The most common side effects of Saroglitazar are gastritis (stomach inflammation), nausea, vomiting, asthenia (weakness), chest discomfort, dizziness, fever, and weakness.
Warnings
Saroglitazar should not be consumed if you are allergic to Saroglitazar or any of its ingredients in the medication. Before using this medicine, let your doctor know if you have any liver or kidney problems or a history of muscle issues. If you have heart disease, be cautious as this medicine hasn't been studied in severe heart failure patients. Although uncommon, watch for rapid weight gain, which may be a sign of swelling and heart-related symptoms. If you experience any concerning symptoms, contact your doctor right away.
Precautions
Before starting the treatment, inform your doctor if you are pregnant, think you may be pregnant, or planning to get pregnant or breastfeeding. The safety and effectiveness of Saroglitazar have not been confirmed for use in children. Patients with liver, heart, and kidney conditions should take Saroglitazar cautiously and should inform the doctor about all the underlying medical conditions.
Word of Advice
Do not discontinue this medicine without your doctor's guidance. Do not take a double dose to compensate for a missed dose. Inform your doctor immediately if you develop any serious side effects. Your doctor will determine whether dose adjustments are necessary. Seek clarification from your doctor regarding any concerns about your treatment. Store this medicine away from the sight and reach of children and pets. Do not freeze this medicine. Check the expiry date before each use.
References
Saroglitazar; [Accessed 20th July 2023]; lipaglyn.com/downloads/Lipaglyn_PI_Booklet.pdf Clinical trials, [Accessed 20th July 2023] https://www.clinicaltrialsarena.com/projects/lipaglyn-saroglitazar-treating-type-ii-diabetes/
Frequently Asked Questions
How to manage the side effects of Saroglitazar?
To manage the side effects of Saroglitazar, follow the prescribed dosage and report side effects promptly. To lower the risk of additional liver damage, maintain a healthy diet and exercise regularly. Monitor your liver function with routine blood tests. If you experience any liver-related pain or discomfort, consult your doctor for guidance.
What are the side effects of Saroglitazar?
Common side effects of Saroglitazar include gastritis (stomach inflammation), nausea, vomiting, asthenia (weakness), chest discomfort, dizziness, fever, and weakness. It is crucial to consult your doctor for any concerns or persistent side effects.
Can you take Saroglitazar when pregnant?
Limited information is available on using Saroglitazar during pregnancy. So consult your medical professional regarding the usage. The potential benefits and risks should be carefully assessed. Your doctor will suggest taking this medicine only if it's necessary.
What should I do if I miss a dose of Saroglitazar?
If you miss a dose of the medicine, take it as soon as possible. However, if it's close to the time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose of the Saroglitazar.
What is Saroglitazar used for?
Saroglitazar is an antidiabetic drug used to treat diabetic dyslipidemia and hypertriglyceridemia in individuals with Type 2 diabetes mellitus, especially when statin therapy is ineffective in controlling these conditions.