DEXLANSOPRAZOLE
Background and Date of Approval
Dexlansoprazole is an antiulcer medication approved by the U.S. Food and Drug Administration for the treatment of Gastroesophageal Reflux Disease (GERD).
Uses
Dexlansoprazole is to treat conditions such as gastroesophageal reflux disease (in which the stomach acid and contents flow back into the esophagus, leading to symptoms like heartburn, regurgitation, and difficulty swallowing), peptic ulcers, and other acid-related disorders.
How is it administered?
Take the Dexlansoprazole as advised by your physician. Do not crush, chew, or open the medicine. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. Only stop taking the tablet if your doctor advises you to stop.
Side Effects
The side effects known to occur commonly during the treatment with Dexlansoprazole are allergic reactions, severe diarrhea, and abdominal discomfort. Some serious side effects include stomach pain, common cold, nausea, vomiting, and flatulence.
Warnings
Contact your physician immediately if you experience allergies to this drug and its ingredients. Individuals with severe liver problems may have impaired liver function, which can affect the metabolism and elimination of Dexlansoprazole. In such cases, the use of this drug may need to be adjusted, or alternative treatment options may be considered. Inform your physician if you have stomach problems, as your doctor may need to adjust your dosage accordingly during these conditions. Do not administer this drug to children or adults under 18 years old.
Precautions
Long-term use of this medicine may result in low magnesium levels in the body (hypomagnesemia). Symptoms of low magnesium levels include fatigue, muscle spasms or weakness, irregular heartbeat, and seizures. If you develop any of these symptoms, notify your doctor immediately. It is necessary to discuss using Dexlansoprazole with your physician if you are pregnant, suspecting pregnancy, or breastfeeding.
Word of Advice
Dexlansoprazole is usually taken at least one hour before meals. Follow the instructions given by your doctor regarding the timing and dosing of this medication. While taking dexlansoprazole, dietary modifications may support your treatment. Avoid foods and beverages that trigger your symptoms, such as spicy or acidic foods, caffeine, and alcohol. Eat smaller meals and avoid eating close to bedtime. Consider elevating the head of your bed to help reduce nighttime acid reflux.
References
Takeda Pharmaceuticals America Inc, US Food and Drug Administration, [ Revised on Jan 2016] [ Accessed on 5th Sep 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/208056lbl.pdf Takeda Pharma A/S, The Health Products Regulatory Authority (HPRA), [ Revised on Jan 2015] [Accessed on 5th Sep 2023], http://www.hpra.ie/img/uploaded/swedocuments/PIL-2159149-15072015133904-635725643461415000.pdf Goodman & Gilmanâs, The Pharmacological Basis of Therapeutics, Pharmacotherapy of acidity, ulcers, and reflux disease, 12th edition, 2011, 1311.
Frequently Asked Questions
What conditions does Dexlansoprazole treat?
Dexlansoprazole is primarily used to treat gastroesophageal reflux disease (GERD), erosive esophagitis, and heartburn caused by acid reflux.
Can I drink alcohol while taking Dexlansoprazole?
It's generally safe to have moderate alcohol consumption while taking Dexlansoprazole. However, excessive alcohol can increase stomach acid production and worsen symptoms, so it's best to limit alcohol intake.
Can I take Dexlansoprazole with food?
Dexlansoprazole is usually taken at least one hour before meals. However, your healthcare provider may give specific instructions based on your condition.
How long does it takes for Dexlansoprazole to start its action?
Dexlansoprazole can relieve symptoms such as heartburn within a few hours of taking the medication. However, the full healing effects may take several days to weeks, depending on the underlying condition being treated.
Can I stop taking Dexlansoprazole once my symptoms improve?
It's important not to stop taking Dexlansoprazole without consulting your doctor, even if your symptoms improve. Abruptly discontinuing the medication can lead to a recurrence of symptoms.