MEBEVERINE

Background and Date of Approval

Mebeverine is an antispasmodic medication approved by the U.S. Food and Drug Administration for the treatment of irritable bowel syndrome (IBS).

Uses

Mebeverine is used to relieve symptoms associated with irritable bowel syndrome (IBS), a common gastrointestinal disorder. It helps to reduce muscle spasms in the intestines, which can lead to abdominal pain, cramps, and discomfort.

How is it administered?

Take the Mebeverine as advised by your physician. Do not crush, chew, or open the medicine. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. Only stop taking the capsule if your doctor advises you to stop.

Side Effects

The side effects known to occur commonly during the treatment with Mebeverine are skin rash, redness, and itchy skin. Some serious side effects include difficulty breathing, and swelling of the face, neck, tongue, or throat.

Warnings

This drug contains sucrose as an inactive ingredient in which the body is unable to digest or process certain types of sugars, which can lead to digestive discomfort, bloating, abdominal pain, and other symptoms. If you have sugar intolerance, inform your doctor before starting this therapy. Limited information is available about the safety of this drug for pregnant women. If you are pregnant or think you might be pregnant, it is necessary to consult your doctor or pharmacist before taking Mebeverine. The use of this drug is not recommended during breastfeeding. If you are breastfeeding or planning to breastfeed, it's important to avoid consuming this drug.

Precautions

Mebeverine should not be taken by individuals who have a known hypersensitivity or allergy to the medication or any of its components. If you fall into this category, it's essential to avoid using this drug and discuss alternative treatment with your physician. If you have liver or kidney problems, it's important to inform your doctor before taking this drug. This medicine is not intended for use in adults and children below 18 years of age.

Word of Advice

No significant interactions are documented between Mebeverine and alcohol or grapefruit juice. However, limiting alcohol consumption and avoiding grapefruit juice during Mebeverine treatment is advisable to maintain therapeutic safety.

References

Aspire Pharma Limited, Electronic Medicines Compendium (EMC), [Revised on Feb 2023] [Accessed on 18th August 2023], https://www.medicines.org.uk/emc/files/pil.8896.pdf Valeria Atenea Costa Barney, Alan Felipe Ovalle Hernández, The role of antispasmodics in managing irritable bowel syndrome, Rev Colomb Gastroenterol, 2019, 34 (3), 267-273, [Accessed on 18th August 2023], http://www.scielo.org.co/pdf/rcg/v34n3/en_0120-9957-rcg-34-03-00269.pdf I.D. Penman, C.W. Lees, Alimentary tract and pancreatic disease, Davidson’s Principles and Practice of Medicine, 22nd Edition, 2014, 837-920.

Frequently Asked Questions

Is Mebeverine effective for everyone with IBS?

Mebeverine can be effective for many individuals with IBS, especially those who experience symptoms related to intestinal muscle spasms. However, its effectiveness may vary from person to person.

What symptoms does Mebeverine treat?

Mebeverine is used to treat symptoms of irritable bowel syndrome (IBS), such as abdominal pain, cramps, bloating, and discomfort. It does not cure IBS but can provide relief from these bothersome symptoms.

Are there any common side effects of Mebeverine?

Common side effects of Mebeverine are generally mild and may include skin rash, redness, and itchy skin. If you experience severe or persistent side effects, contact your doctor.

Is Mebeverine safe while breastfeeding?

Mebeverine should not be used during breastfeeding. It's important to avoid it while nursing to prevent potential effects on the nursing infant.

Can Mebeverine interact with other medications?

Inform your doctor about all medications, supplements, and herbal products you are taking. Although interactions are rare, it's best to ensure there are no potential conflicts.

Available Brands 9

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS