TELMISARTAN
Background and Date of Approval
The U.S. FDA approved Telmisartan for hypertension and cardiovascular disease on November 17, 2000. Telmisartan is an antihypertensive agent belonging to the angiotensin II receptor antagonist class of medications. Angiotensin II is a naturally occurring substance that constricts blood vessels, raising blood pressure.
Uses
Telmisartan treats high blood pressure ( essential hypertension) in adults. It is specifically used for hypertension, not caused by any other underlying condition. It functions by inhibiting the effects of angiotensin II, causing the blood vessels to relax and decreasing blood pressure. Additionally, it is also used to reduce cardiovascular ( stroke, heart attack, or failure) conditions in adults.
How is it administered?
Take the Telmisartan tablet as your physician advises. Usually, it is taken once a day. Take medicine at the same time. Do not crush, chew, or open the medicine. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. Only stop taking the tablet if your doctor advises you to stop.
Side Effects
The most common side effects of Telmisartan are low blood pressure, back pain, sinusitis, and diarrhea. Serious side effects while taking Telmisartan are sepsis (blood poisoning) and angioedema (swelling in the deeper layers of the skin).
Warnings
Do not consume Telmisartan if you are allergic to Telmisartan and its other ingredients. Also, do not consume if you have severe liver (cholestasis or biliary obstruction) conditions, diabetes, or impaired kidney function, which was treated with pressure-lowering medicine with aliskiren. Telmisartan is not recommended during early pregnancy and should not be taken beyond the first three months as it may harm the unborn baby.
Precautions
Inform your doctor if you are older or need any dose adjustments. Notify your doctor if you are pregnant, planning to get pregnant, or think you may be pregnant or breastfeeding. This medicine should be only used for hypertension conditions in adolescents and children from 6 - 17 years of age. Do not consume grapefruit juice or grapefruit while taking this tablet. It is not suggested to use this medicine under the age of 6 years because it has yet to be studied.
Word of Advice
Patients with liver disease or heart disease should use Telmisartan with caution and inform their doctor of all underlying medical conditions. Do not discontinue the medicine without medical advice. Do not take a double dose to compensate for a missed dose. Inform your doctor if you experience any serious side effects. Your doctor will advise on any necessary dose adjustments. Consult your doctor for further information. Avoid grapefruit and grapefruit juice. Keep the medicine out of sight and reach of children and pets. Do not freeze the medicine. Store below 25°C. Always verify the expiry date before use.
References
Glenmark Pharmaceuticals Europe Limite., Electronic medicines compendium (emc), [Revised on November 2019] [ Accessed on 30th May 2023], 13 Product Information (medicines.org.uk) Hetero labs limited, US Food and Drug Administration, [Revised on august 2025] [Accessed on 30th May 2023], 205901Orig1s000lbl.pdf (fda.gov)
Frequently Asked Questions
How to manage the side effects of Telmisartan?
To manage the side effects of Telmisartan, follow the prescribed dosage, and report side effects promptly. Stay hydrated, and monitor blood pressure regularly. Maintain a healthy lifestyle, and attend follow-up appointments.
Can I dissolve the Telmisartan and drink it instead of swallowing it?
No, you should not dissolve the tablet and drink the solution. This medicine was designed to be swallowed whole with water. It's mandatory to follow the instructions provided by your healthcare provider to avoid the side effects of Telmisartan.
Are there any serious side effects of Telmisartan I should be aware of?
Yes, side effects of Telmisartan may include severe allergic reactions and liver or kidney problems. It is mandatory to seek medical attention if you encounter any side effects, such as difficulty breathing, swelling, nausea, and rashes.
Can I use a Telmisartan for children?
Telmisartan should not be used in adolescents and children until 18 years are not recommended.
Is it safe to use Telmisartan if I am two months pregnant?
Telmisartan is not recommended during early pregnancy and should not be taken beyond the first three months as it may harm the unborn baby. Report to your medical professional if you are pregnant, think you may be pregnant, or planning for the pregnancy before starting the treatment.